Pre-hospital plasma transfusion in patients at risk of hemorrhagic shock decreases mortality
1. In patients at risk of hemorrhagic shock, the pre-hospital administration of thawed plasma decreased mortality at 24 hours and...
ECMO for severe ARDS does not improve mortality
1. Extracorporeal membrane oxygenation (ECMO) for severe acute respiratory distress syndrome (ARDS) did not show a 60-day mortality benefit compared...
Hydrocortisone plus fludrocortisone decreases mortality in adults with septic shock
1. Patients with septic shock in the intensive care unit (ICU) undergoing mechanical ventilation receiving hydrocortisone plus fludrocortisone had a...
Adjunctive glucocorticoid therapy does not lower mortality in septic shock
1. Patients with septic shock in the intensive care unit (ICU) undergoing mechanical ventilation and managed with adjunctive continuous hydrocortisone...
Multiple myeloma management with lenalidomide, bortezomib and dexamethasone associated with prolonged progression-free survival
1. The use of lenalidomide, bortezomib and dexamethasone (RVD) with transplantation was associated with a significantly longer progression-free survival compared...
Adding antiandrogen therapy to radiation improves overall survival in recurrent prostate cancer
1. The addition of biclutamide (antiandrogen) to radiation therapy for recurrent prostate cancer improved overall survival compared to radiation alone....
![Galangin may sensitize apoptosis-resistant renal carcinoma cells [PreClinical]](https://www.2minutemedicine.com/wp-content/uploads/2016/01/Papillary_renal_cell_carcinoma_-_very_high_mag-350x250.jpg)
Sunitinib increases disease free survival in high risk renal carcinoma post nephrectomy
1. In patients with locoregional clear-cell renal cell carcinoma (RCC) at high risk of recurrence post nephrectomy, those taking sunitinib...
Adding daratumumab increases progression free survival in multiple myeloma
1. The addition of daratumumab to standard therapy of lenalidomide and dexamethasone increased progression-free survival in relapsed or refractory multiple...
Rituximab improves survival in B-cell lineage acute lymphoblastic leukemia
1. Compared to standard chemotherapy alone, the addition of the rituximab significantly improves event-free survival among adults with CD20-positive, Philadelphia...
![Reduced neuronal BRCA1 associated with decreased DNA repair in Alzheimer’s disease [PreClinical]](https://www.2minutemedicine.com/wp-content/uploads/2015/12/DNA_Furchen_edited-350x250.png)
Higher incidence of germline DNA-repair mutations in men with metastatic prostate cancer
1. Men with metastatic prostate cancer had a significantly higher incidence of germline mutations mediating DNA-repair processes compared to men...