Tag: proton pump inhibitor (PPI)

1. Lansoprazole was not found to be efficacious in the treatment of persistent throat symptoms. Evidence Rating Level: 1 (Excellent) Persistent throat symptoms are frequently encountered in primary and secondary care settings. These symptoms may include voice hoarseness, the feeling of a lump in the throat, continuously clearing the throat, and...

1. The use of proton pump inhibitors (PPIs) in a large pediatric cohort resulted in a small but statistically significant increase in fracture risk compared to children who were not using PPIs. Evidence Rating Level: 2 (Good) Proton pump inhibitors (PPIs) are the primary treatment for gastric acid-related disorders in children, despite...

Clinical Course and Risk Factors for Mortality of Adult Inpatients With COVID-19 In Wuhan, China: A Retrospective Cohort Study 1. In-hospital COVID-19-related death was associated with older age, d-dimer levels greater than 1.0μg/mL, and higher Sequential Organ Failure Assessment upon assessment. 2. Median viral shedding in survivors was 20 days but...

Proton pump inhibitors (PPIs) are widely used in the management of gastroesophageal reflux. However, several studies have demonstrated serious adverse events associated with PPI use including cardiovascular disease, acute kidney injury, chronic kidney disease, dementia, pneumonia, gastric cancer, Clostridium difficile infection, and increased risk of fracture. Recent evidence has...

Ultra-processed food intake and risk of cardiovascular disease: prospective cohort study (NutriNet-Santé) The consumption of ultra-processed food has increased substantially over the last several decades. These foods often have higher proportions of total and saturated fat, added sugar, energy density and salt, and lower proportions of fibre and vitamin density....