Tag: seizures

1. Expert review of smartphone videos possesses additive, predictive value for the diagnosis of epileptic seizures, with the ability to maintain confidentiality in the sharing of these files. Evidence Rating Level: 2 (Good) Video electroencephalogram (EEG) monitoring (VEM) is the ideal diagnostic standard for epileptic seizures when diagnosis is unclear through medical...

Electronic Cigarette and JUUL Use Among Adolescents and Young Adults 1. The use of electronic cigarettes is highly prevalent among adolescents and young adults through the advent of JUUL, which has unique implications for this young and susceptible age group. Evidence Rating Level: 1 (Excellent) Adverse effects of nicotine on overall health,...

Cortical stimulation during intracranial electroencephalography (EEG) is used in defining the epileptogenic zone in patients with epilepsy, with the aim of removing the seizure onset zone (SOZ). However, the effect of cortical stimulation on surgical outcomes has not been well studied. In this cohort study, investigators performed neurophysiologic characterization...

The safety and immunogenicity of two novel live attenuated monovalent (serotype 2) oral poliovirus vaccines in healthy adults: a double-blind, single-centre phase 1 study Oral live-attenuated polio vaccines (OPV) and injected inactivated polio vaccines IPV) have helped eradicate wild polioviruses. However, there is still a need to develop new vaccines...

1. Amongst adults and children with the Lennox-Gastaut (LG) syndrome, addition of cannabidiol to a conventional antiepileptic regimen reduced drop seizure frequency compared to placebo treated patients. 2. The most common adverse events amongst patients treated with cannabidiol were diarrhea, somnolence, and decreased appetite. These effects were dose-dependent. Evidence Rating Level:...

1. In a Norwegian nationwide registry study, children with epilepsy were compared to the general population. Over three-quarters of children with epilepsy had at least 1 comorbid neurologic, medical, or psychologic disorder compared to less than a third in the general population. 2. Children with more complicated epilepsies had even...

Originally published by Harvard Health. What Is It? The brain's nerve cells (neurons) communicate by firing tiny electric signals. During a seizure (convulsion), the firing pattern of these electric signals suddenly changes. It becomes unusually intense and abnormal. A seizure can affect a small area of the brain. Or it can affect...

1. The majority of children (65%) diagnosed with new-onset epilepsy related to the administration of vaccinations were found to have an underlying genetic or structural neurological disorder which predisposed them to developing epilepsy.  2. The etiologies for underlying epilepsy disorders unmasked by vaccination included: chromosomal deletions, neuronal migration disorders, Dravet...

1. A daily low-dose fish oil regimen was associated with fewer monthly seizures in patients with drug-resistant epilepsy. 2. High-dose fish oil regimen was paradoxically not associated with a lower seizure frequency. Evidence Rating Level: 1 (Excellent) Study Rundown: Approximately 1 out of every 5 epilepsy patients have drug-resistant...

Image: PD 1. Lacosamide functions well as an add-on anti-epileptic drug (AED), decreasing frequency of seizures in 66% of patients with brain tumors. 2. Lacosamide is well tolerated with the majority (77%) of patient experiencing no side effects. This retrospective study demonstrates the potential for lacosamide to be effective and safe as...