Tag: STEMI

1. In this retrospective analysis of patients 75-years or older with ST-elevation myocardial infarction (STEMI) and cardiogenic shock, use of percutaneous coronary intervention (PCI) was associated with lower in-hospital mortality. 2. The use of PCI for older patients with STEMI and shock increased during the study period. Evidence Rating Level: 2...

1. In this randomized controlled trial, low-dose intracoronary alteplase given early during primary percutaneous coronary intervention (PCI) for acute ST-Elevation Myocardial Infarction (STEMI) did not reduce microvascular obstruction. 2. Health related quality of life was not improved with low-dose intracoronary alteplase. Evidence Rating Level: 1 (Excellent) Study Rundown: Acute coronary thrombosis causes...

Ischemic heart disease, the most common cause of morbidity and mortality worldwide, has many modifiable and non-modifiable risk factors, including several external factors. This retrospective observational study aimed to investigate circadian rhythms, major sports events, and national holidays as potential triggers of myocardial infarction. Investigators reviewed 283,014 cases of...

1. Based on data from the Acute Coronary Treatment and Intervention Outcomes Network Registry–Get With the Guidelines (ACTION Registry-GWTG), only one-half of all patients who required transfer for STEMI received primary percutaneous coronary intervention (pPCI) within 120 minutes. As the drive time increased to between 30 and 120 minutes,...

1. This meta-analysis of outcomes after primary percutaneous coronary intervention for ST-segment elevation myocardial infarction (STEMI) showed that women fared similarly to men in terms of hospital mortality and 1-year mortality, after adjusting for major confounding variables. 2. There were major differences in the baseline characteristics between women and men,...

1. Using cardiac magnetic resonance imaging (MRI), an association was found between infarct severity in patients with reperfused ST segment elevation myocardial infarction (STEMI) and poorer functional recovery of the left ventricle (LV). 2. Cardiac biomarker assessment showed that the presence of microvascular obstruction (MVO) and intramyocardial hemorrhage (IMH)...

1. Patients with STEMI who underwent coronary artery thrombus aspiration before PCI did not have a significant reduction in mortality at 1 year of follow up. 2. Patients with STEMI who underwent thrombus aspiration before PCI did not have a significant reduction in the incidence of the composite of...

Image: PD  1. Bivalirudin, initiated during transport for primary PCI in patients with STEMI, improved 30-day clinical outcomes with a reduction in major bleeding.  2. The risk of acute stent thrombosis was higher with bivalirudin, compared to unfractionated or low-molecular-weight heparin and optional glycoprotein IIb/IIIa inhibitors.  Evidence Rating Level: 1 (Excellent)  Study Rundown:...

Image: PD In this section, we will highlight the key high-impact studies, updates, and analyses published in medicine during the past week. Door-to-Balloon Time and Mortality among Patients Undergoing Primary PCI For ST elevation myocardial infarctions (STEMI), percutanous coronary intervention (PCI) is recommend with strong evidence for benefit for a door-to-balloon time...