Tag: surfactant

1. The intubation-recruitment-surfactant administration-extubation procedure reduced the need for invasive ventilation in extremely preterm neonates compared to those not receiving lung recruitment. 2. There were no adverse effect on safety outcomes including in-hospital mortality, pneumothorax and intraventricular hemorrhage. Evidence Rating Level: 1 (Excellent) Study Rundown: Early surfactant administration is the most...
1. In patients with pulmonary alveolar proteinosis, use of twice daily inhaled granulocyte-macrophage colony-stimulating factor (GM-CSF) did not improve clinical outcomes of vital capacity or functional walk test compared to placebo treated patients. 2. Laboratory and imaging metrics suggestive of reduced pulmonary disease were noted in GM-CSF treated patients. Evidence Rating...
1. In patients with pulmonary alveolar proteinosis, use of twice daily inhaled granulocyte-macrophage colony-stimulating factor (GM-CSF) did not improve clinical outcomes of vital capacity or functional walk test compared to placebo treated patients. 2. Laboratory and imaging metrics suggestive of reduced pulmonary disease were noted in GM-CSF treated patients. Evidence Rating...
Image: PD 1. Among 10 infants treated for respiratory distress syndrome with artificial surfactant in this landmark trial, significant improvements in blood pressure, acid-base status, arterial oxygenation, and radiologic findings were observed. 2. Infants also required significantly less oxygen therapy and ventilator pressure following surfactant administration. Original Date of Publication: January 1980 Study...
Image: PD 1. From 2000 to 2009, neonatal intensive care units (NICUs) increased use of antenatal steroids, cesarean delivery, surfactant in the delivery room, and less-invasive respiratory support for very low birth weight infants (VLBW).  2. Decreases in steroid use for chronic lung disease, delayed surfactant use, and endotracheal tube ventilation...