Tag: vaccination

1. The majority of children (65%) diagnosed with new-onset epilepsy related to the administration of vaccinations were found to have an underlying genetic or structural neurological disorder which predisposed them to developing epilepsy.  2. The etiologies for underlying epilepsy disorders unmasked by vaccination included: chromosomal deletions, neuronal migration disorders, Dravet...
1. N. meningitidis is a bacterium responsible for meningitis, bacteremia, and pneumonia, with potentially lethal and long term sequelae. 2. The American Academy of Pediatrics (AAP) has adjusted its vaccination guidelines to include two newly licensed conjugate vaccines, Hib-MenCY-TT and MenACWY-CRM, in an effort to address immunization of younger children...
1. There is strong evidence that the measles/mumps/rubella (MMR) vaccine is not linked to autism but that it is linked to a risk of febrile seizures. 2. There is moderate evidence that links the rotavirus vaccination to a risk of intussusception and the hepatitis A vaccine to purpura. 3. There is...
Image: PD 1. After implementation of varicella vaccination in children in 1995, the incidence of varicella decreased by approximately 90 to 95% in children between the ages of 5 to 19, with no shift of disease burden to older age groups. 2. There was a 90% reduction in varicella hospitalization rates...
Image: PD 1. Compared with pre-vaccine rates, this retrospective study found rotavirus-coded hospitalizations decreased as rotavirus vaccination rates of US children increased. 2. Increased rotavirus vaccination use was associated with decreased rates of diarrhea-related health care utilization by both vaccinated and unvaccinated children. Evidence Rating Level: 2 (Good) Study Rundown: Until the routine...
Image: PD 1. Vaccinations administered in the first year of life were not associated with increased risk of post-vaccination seizures, regardless of whether they were on-time or delayed. 2.  Delaying administration of measles-containing vaccinations after 15 months of age increased risk of post-vaccination seizures compared to on-time vaccination; the highest risk...
Image: PD 1. Seroprotection after a challenge dose of hepatitis B (HB) vaccine was observed in 92% of adolescents (16-19 years) who had received the HB vaccine series as an infant. 2. Higher geometric mean anti-HB surface antigen antibody titers were seen after challenge with HB vaccine in adolescents whose infant...
Image: PD 1. Trivalent influenza vaccine (TIV) was found to be 85.5% effective in children aged 6 months to 2 years. 2. TIV was more effective against influenza A than influenza B among children aged 6 months to 5 years. Evidence Rating Level: 2 (Good) Study Rundown: Annual influenza vaccination is the mainstay...
Classics Series, Landmark Trials in Medicine
Image: PD 1. Among children born in Denmark during a 7-year study period, no increase in risk of developing autism was seen in those who were vaccinated against measles, mumps, and rubella relative to unvaccinated children. Original Date of Publication: November 2002 Study Rundown: As the incidence of autism increased in the...
Image: PD 1. Children given their first of two measles vaccines at 15 months of age or older had a significantly lower risk of measles infection during a recent epidemic than those given their first dose at 12 or 13 months. 2. Timing of the second dose of measles vaccine did...