Tag: vaccination

 1. Doses of recommended non-influenza vaccines administered to children of all age groups decreased significantly in Southern California following the stay-at-home order at the beginning of the COVID-19 pandemic. 2. During the recovery phase of the pandemic, weekly vaccination rates recovered quickly in children younger than 24 months, but remained significantly...
1. Over a mean follow-up period of 3.6 years, no significant association was detected between maternal influenza vaccination during pregnancy and early childhood health outcomes including pediatric asthma, neoplasms and sensory impairment. Evidence Rating: 2 (Good) Study Rundown: Vaccine hesitancy, particularly during pregnancy and early childhood, is a key issue that...
1. The initial doses of the Pfizer and AstraZeneca vaccines were 91% and 88% efficacious in reducing COVID-19 hospitalizations one month after vaccination. 2. Combined vaccine efficacy of the Pfizer and AstraZeneca in preventing hospital admission due to COVID-19 among those aged 80 years and older was approximately 83%. Evidence Rating...
1. The ChAdOx1 nCov-19 (AstraZeneca) vaccine was not effective for the prevention of mild-to-moderate COVID-19 infection caused by the B.1.351 variant.  2. The ChAdOx1 nCov-19 vaccine was effective against mild-to-moderate non-variant COVID-19 infection after a single injection. Evidence Rating Level: 1 (Excellent)      Study Rundown: With the emergence of COVID-19 variants, there is the...
1. No significant increase in spontaneous abortion, preterm birth, major structural defects, or small for gestational age rates were found in women receiving 9vHPV vaccine during pregnancy (within 19 weeks pregnant). 2. No significant differences were found in adverse birth outcomes when comparing vaccinations in women 22 weeks before last...
1. The plant-based quadrivalent virus-like particle (QVLP) seasonal influenza vaccine provided strong protection against respiratory illness and influenza-like illness. 2. The QVLP vaccine had a similar safety profile to other current non-living influenza vaccines, with the vast majority of adverse events being mild to moderate. Evidence Rating Level: 1 (Excellent) Study Rundown:...
1. With 70% vaccination coverage, a 3rd trimester maternal vaccine for respiratory syncytial virus (RSV) was modelled to reduce RSV infection rates by 16.6% in infants younger than 3 months.  2. Incidence rate of RSV infections in the first 6 months of life for infants born to unvaccinated mothers was...
Advance care planning in patients with advanced cancer: A 6-country, cluster-randomised clinical trial 1. An advanced care planning (ACP) intervention was not found to increase quality of life compared to usual care, in patients with advanced lung or colorectal cancer. 2. ACP was found to increase the number of patients receiving...
1. Postmarketing surveillance programs of Food and Drug Administration approved vaccines were the most common source of safety data triggering safety label changes. 2. The most common safety label changes included changes in population restrictions and allergies. Evidence Rating Level: 3 (Average) Study Rundown: Food and Drug Administration (FDA) approved vaccines undergo...
1. In this retrospective populated-based cohort study, the annual inactivated influenza intramuscular vaccination was associated with a small absolute increase in subdeltoid bursitis. 2. When compared to nurses, vaccination by medical assistants may be associated with increased risk of vaccination attributable bursitis. Evidence Rating Level: 2 (Good) Study Rundown: Vaccination induced bursitis...