• About
  • Masthead
  • License Content
  • Advertise
  • Submit Press Release
  • RSS/Email List
  • Write for us
  • Contact us
2 Minute Medicine
No Result
View All Result

No products in the cart.

SUBSCRIBE
  • Specialties
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • The Scan
  • Wellness
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • AccountLog-in/out
    • Subscribe
    • Sign-in
    • My account
2 Minute Medicine
  • Specialties
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • The Scan
  • Wellness
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • AccountLog-in/out
    • Subscribe
    • Sign-in
    • My account
SUBSCRIBE
2 Minute Medicine
Subscribe
Home All Specialties Cardiology

Urine albumin excretion in black adults linked to higher risk of coronary heart disease

bys25qthea
August 22, 2013
in Cardiology, Chronic Disease, Nephrology
Reading Time: 3 mins read
0
Share on FacebookShare on Twitter

Image: PD

1. Urinary albumin excretion serves as a proxy for kidney damage and has been linked to higher rates of coronary heart disease. 

2. Black adults had a higher risk of incident coronary heart disease events with increased urinary albumin excretion when compared to white adults. 

Evidence Rating Level: 1 (Excellent) 

Study Rundown: This study is an offshoot of the Reasons for Geographic and Racial Differences in Stroke (REGARDS) study. The authors of this study have previously demonstrated that the albumin-to-creatinine ratio (ACR) was linked to higher rates of incident stroke in black adults as compared white adults. This current study sought to determine if the disparity extended to coronary heart disease (CHD) as well. ACR is regarded as a good measure of kidney injury and an increased ACR, greater than 30mg/g, is also considered a risk factor for cardiovascular disease.

It was found that after controlling for socioeconomic factors, medication use, and co-morbid conditions, higher ACRs were associated with greater risk of incident CHD events in black adults. Interestingly, recurrent CHD events were not associated with higher ACRs in neither black nor white adults. Explanations of the findings include increased susceptibility to vascular injury in black individuals as well as the relative poor preventative care available among the black population. Since kidney function has been related to heart disease it is also possible that differences in the rate of progression of kidney disease could have led to the findings. Causes of error endogenous to the data and study design may be related to the relatively low number of CHD cases in white males as well as a higher proportion of black adults in the highest ACR category.

Click to read the study in JAMA

RELATED REPORTS

The 2 Minute Medicine Podcast Episode 5

The Scan by 2 Minute Medicine®: the Future of Medicine, Neuralink, the Spotlight on Celine Dion and COVID-19 on Social Media

The 2 Minute Medicine Podcast Episode 4

Click to read an accompanying editorial in JAMA

Relevant Reading: Association of estimated glomerular filtration rate and albuminuria with all-cause mortality in general population cohorts

In-Depth [prospective cohort study]: This study included 23,273 participants without CHD and 4,934 patients with CHD. Participants were stratified by ACR level, less than 10mg/g, between 10-29.9 mg/g, 30-300 mg/g, and greater than 300 mg/g. Incidence rate ratios (IRRs) were increased at even the second lowest category, 10-29.9 mg/g ACR, in both blacks (2.20, CI 1.61-3.02) and whites (1.48, CI 1.15-1.90). After adjusting for age, sex, region, co-morbid condition, biochemical measures such as glomerular filtration rate, c-reactive protein and high-density lipoprotein, and medicine use, only black adults had an increasing risk of CHD events (1.84, CI 1.34-2.53) and association with ACR levels greater than 10mg/g (p=0.03). Black participants with an ACR >300mg/g, when compared to black participants with a ACR <10mg/g, had 3 times the risk of incident CHD. Interestingly, neither black nor white patients with previous CHD events (p=0.53) demonstrated an association between increasing ACR and risk of CHD.

By Ravi Shah and Brittany Hasty 

More from this author: Reducing intake of sugary drinks has effect on BMI while intervention is maintained, Terminal cancer patients hold misconceptions of the role of chemotherapy, Home-based walking program an effective treatment for peripheral artery disease, Androgen deprivation therapy increases risk of acute kidney injury in patients with prostate cancer

© 2013 2minutemedicine.com. All rights reserved. No works may be reproduced without written consent from 2minutemedicine.com. Disclaimer: We present factual information directly from peer reviewed medical journals. No post should be construed as medical advice and is not intended as such by the authors or by 2minutemedicine.com. PLEASE SEE A HEALTHCARE PROVIDER IN YOUR AREA IF YOU SEEK MEDICAL ADVICE OF ANY SORT. Content is produced in accordance with fair use copyrights solely and strictly for the purpose of teaching, news and criticism. No benefit, monetary or otherwise, is realized by any participants or the owner of this domain. 

Tags: albuminheart diseasekidney
Previous Post

Low circulating cholesterol in neonates linked with pyloric stenosis

Next Post

Haloperidol for ICU delirium: No effect on duration or incidence versus placebo

RelatedReports

2MM Podcast

The 2 Minute Medicine Podcast Episode 5

January 2, 2023
The Scan by 2 Minute Medicine®:  Ultra-Trail du Mont-Blanc, Taylor Swift, NBA rookie Chet Holmgren and Magic Mushrooms!
The Scan by 2 Minute Medicine®

The Scan by 2 Minute Medicine®: the Future of Medicine, Neuralink, the Spotlight on Celine Dion and COVID-19 on Social Media

December 27, 2022
2MM Podcast

The 2 Minute Medicine Podcast Episode 4

December 15, 2022
The Scan by 2 Minute Medicine®:  Ultra-Trail du Mont-Blanc, Taylor Swift, NBA rookie Chet Holmgren and Magic Mushrooms!
The Scan by 2 Minute Medicine®

The Scan by 2 Minute Medicine®: the New Cost of Insulin, Beyond IVF, the Spotlight on RSV and Influenza, and Theranos Founder Sentenced to 11 Years!

November 30, 2022
Next Post
Clinical impression not reliable in identifying drug-seeking behavior

Haloperidol for ICU delirium: No effect on duration or incidence versus placebo

Low diastolic blood pressure associated with higher mortality in chronic kidney disease

Low diastolic blood pressure associated with higher mortality in chronic kidney disease

Insecticidal bed nets linked with reduced transmission of lymphatic filariasis

Insecticidal bed nets linked with reduced transmission of lymphatic filariasis

License Our Award-Winning Physician-Written Medical News and Visual Abstracts

2 Minute Medicine is the leading authoritative medical news licensing service, and the only with reports written by practicing doctors.

LICENSE CONTENT

2MM+ Premium Access

No ads & unlimited access to all current reports, over 9000 searchable archived reports, visual abstracts, Weekly Rewinds, and the online edition of The Classics Series™ textbook.

Subscription Options
2 Minute Medicine

2 Minute Medicine® is an award winning, physician-run, expert medical media company. Our content is curated, written and edited by practicing health professionals who have clinical and scientific expertise in their field of reporting. Our editorial management team is comprised of highly-trained MD physicians. Join numerous brands, companies, and hospitals who trust our licensed content.

Recent Reports

  • The Scan by 2 Minute Medicine®: Maternity Leave Left Out, Dry January, A Measles Resurgence, Dr. GPT
  • Former professional football players may be at greater risk of chronic disease
  • Low-dose pirfenidone may be noninferior to standard dosing in patients with idiopathic pulmonary fibrosis
License Content
Terms of Use | Disclaimer
Cookie Policy
Privacy Statement (EU)
Disclaimer

© 2021 2 Minute Medicine, Inc. - Physician-written medical news.

  • Specialties
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • The Scan
  • Wellness
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • Account
    • Subscribe
    • Sign-in
    • My account

© 2021 2 Minute Medicine, Inc. - Physician-written medical news.

Want more physician-written
medical news?

Join over 10 million yearly readers and numerous companies. For healthcare professionals
and the public.

Subscribe for free today!

Subscription options