• About
  • Masthead
  • License Content
  • Advertise
  • Submit Press Release
  • RSS/Email List
  • Write for us
  • Contact us
2 Minute Medicine
No Result
View All Result

No products in the cart.

SUBSCRIBE
  • Specialties
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • Wellness
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • AccountLog-in/out
    • Subscribe
    • Sign-in
    • My account
2 Minute Medicine
  • Specialties
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • Wellness
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • AccountLog-in/out
    • Subscribe
    • Sign-in
    • My account
SUBSCRIBE
2 Minute Medicine
Subscribe
Home StudyGraphics

#VisualAbstract: Myomectomy associated with better fibroid-related quality of life versus uterine-artery embolization

byConstance Wu
August 5, 2020
in StudyGraphics
Reading Time: 2 mins read
0
Share on FacebookShare on Twitter

1. While women in both groups experienced dramatic gains in fibroid-related quality of life, the magnitude of the increase was greater in the myomectomy group versus the embolization group.

2. Surgical reintervention was necessary in a greater percentage of the embolization group.

Evidence Rating Level: 1 (Excellent)

Study Rundown: Uterine fibroids are the most common tumor type among women of reproductive age and are associated with considerable morbidity if left untreated. Surgical intervention has historically been the mainstay of the management of fibroids, but uterine-artery embolization has more recently become known as a viable treatment alternative that is performed under local anesthesia, resulting in shorter hospital stays and faster recovery. However, studies comparing the efficacy of these two measures have yielded inconclusive results, indicating the need for further research. This study involving women with symptomatic uterine fibroids in the United Kingdom utilized a 100-point disease-specific questionnaire to evaluate fibroid-related quality of life following either procedure. At 2 years, those who underwent myomectomy had a score that was 6 to 8 points better, on average, than those who underwent uterine-artery embolization after adjusting for the baseline score. Perioperative or postoperative complications occurred in roughly one-quarter of women in both groups, but only 1 intraoperative complication occurred in each group. Nearly 10% more women in the embolization group required additional procedures compared to the myomectomy group, but no differences between groups were observed in menstrual bleeding or in the levels of biomarkers of ovarian reserve. This study had good generalizability owing to its multicenter design and broad inclusion criteria, but it was limited by its reliance on imputation due to a relatively high attrition rate and a substantial amount of missing data from patients who did respond to the questionnaire.

Click here to read the study, published today in NEJM

Relevant Reading: Reintervention Rates After Myomectomy, Endometrial Ablation, and Uterine Artery Embolization for Patients with Uterine Fibroids

In-Depth [randomized controlled trial]: This open-label study was conducted at 29 hospitals in the UK between February 2012 and May 2015. 254 women were randomly assigned in a 1:1 ratio to receive either uterine-artery embolization or myomectomy for one or more fibroids. At baseline, the two groups were well-matched for demographic and clinical characteristics including the severity and distribution of fibroids. Following the procedure, participants were asked to submit responses to the Uterine Fibroid Symptom and Quality of Life (UFS-QOL) questionnaire at 6 months, 1 year, and 2 years. Improvement in fibroid-related quality of life was significantly greater in the myomectomy group at all three time points (difference at 6 months, 7.4 points; 95% CI at 6 months, 0.5 to 14.2; difference at 1 year, 10.8 points; 95% CI at 1 year, 4.2 to 17.5; difference at 2 years, 8.0; 95% CI at 2 years, 1.8 to 14.1). Perioperative and postoperative complications occurred in 27 of 113 women (24%) in the uterine-artery embolization group and in 34 of 118 women (29%) in the myomectomy group (relative risk, 1.2; 95% CI, 0.8 to 1.9; P=0.40), and additional fibroid-related procedures were performed in 18 women (16%) in the embolization group and 8 women (7%) in the myomectomy group. Overall, these findings suggest that myomectomy offers sustained health-related quality of life benefits over uterine-artery embolization.

RELATED REPORTS

#VisualAbstract: Relugolix combination therapy led to reduction in uterine fibroid symptoms

Relugolix combination therapy led to reduction in uterine fibroid symptoms

Myomectomy associated with better fibroid-related quality of life versus uterine-artery embolization

©2020 2 Minute Medicine, Inc. All rights reserved. No works may be reproduced without expressed written consent from 2 Minute Medicine, Inc. Inquire about licensing here. No article should be construed as medical advice and is not intended as such by the authors or by 2 Minute Medicine, Inc.

Tags: Fibroidsmyomectomyuterine fibroiduterine-artery embolization
Previous Post

Breastfeeding recommended as primary neonatal analgesic in low resource settings

Next Post

Anti-anaerobic therapy over-prescribed for patients with aspiration community-acquired pneumonia

RelatedReports

#VisualAbstract: Cemiplimab monotherapy significantly improves outcomes in patients with advanced non-small-cell lung cancer with PD-L1 of at least 50%
StudyGraphics

#VisualAbstract: Relugolix combination therapy led to reduction in uterine fibroid symptoms

March 5, 2021
Simvastatin associated with slowed fibroid growth in mice
Obstetrics

Relugolix combination therapy led to reduction in uterine fibroid symptoms

February 27, 2021
Elagolix with add-back hormone therapy effective in reducing fibroid-associated menstrual bleeding
Obstetrics

Myomectomy associated with better fibroid-related quality of life versus uterine-artery embolization

July 30, 2020
Health A to Z

Patient Basics: Fibroids

November 30, 2014
Next Post
Prescription of antibiotics for acute respiratory infections increasing

Anti-anaerobic therapy over-prescribed for patients with aspiration community-acquired pneumonia

Metformin associated with retention of cognitive ability and reduced white matter loss in pediatric brain tumor survivors

Large proportion of late preterm infants and older admitted to the NICU

Characteristics of COVID-19 in febrile infants 2 months of age and younger

License Our Award-Winning Physician-Written Medical News and Visual Abstracts

2 Minute Medicine is the leading authoritative medical news licensing service, and the only with reports written by practicing doctors.

LICENSE CONTENT

2MM+ Premium Access

No ads & unlimited access to all current reports, over 9000 searchable archived reports, visual abstracts, Weekly Rewinds, and the online edition of The Classics Series™ textbook.

Subscription Options
2 Minute Medicine

2 Minute Medicine® is an award winning, physician-run, expert medical media company. Our content is curated, written and edited by practicing health professionals who have clinical and scientific expertise in their field of reporting. Our editorial management team is comprised of highly-trained MD physicians. Join numerous brands, companies, and hospitals who trust our licensed content.

Recent Reports

  • Provision of 1-year mortality data for patients hospitalized with heart failure does not influence clinical decision-making – The REVEAL-HF trial
  • Genetic risk for hemochromatosis associated with abnormal iron deposition localized to motor circuits of the brain
  • Graded sensorimotor retraining may improve chronic lower back pain compared to sham procedure: The RESOLVE randomized clinical trial
License Content
Terms of Use | Disclaimer
Cookie Policy
Privacy Statement (EU)
Disclaimer

© 2021 2 Minute Medicine, Inc. - Physician-written medical news.

  • Specialties
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • Wellness
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • Account
    • Subscribe
    • Sign-in
    • My account

© 2021 2 Minute Medicine, Inc. - Physician-written medical news.