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EvidencePulse™ by 2 Minute Medicine 2026 evidence scan 3 reports You asked top stroke trials 2026 Synthesizing medical evidence... Top 2026 stroke trial results: OCEANIC — ischemic stroke: 6.2% vs 8.4% OPTION* — mRS 0–1: 43.6% vs 34.2% ORIENTAL* — mRS 0–2: 58.6% vs 46.6% *Higher sICH in intervention arms Participants randomizedN OCEANIC 12,327 OPTION 570 ORIENTAL 564 Ask about guidelines or landmark trials... ↑ Try EvidencePulse™ Ask the evidence.
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#VisualAbstract: Previsit Screening for Parental Vaccine Hesitancy

byConstance Wu
November 16, 2019
in StudyGraphics
Reading Time: 2 mins read
#VisualAbstract: Previsit Screening for Parental Vaccine Hesitancy
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1. In this cluster randomized controlled trial, researchers found that informing providers of which parents identified as vaccine hesitant on a standard screening survey had no impact on the length of time the children of these parents remained under-immunized.

2. Researchers also completed a per protocol analysis, studying only parents who completed both visits of the study design. They found a persistent significant increase in the under-immunized time of children whose parents were vaccine hesitant when physicians were made aware of their parents’ vaccine hesitancy.

Evidence Rating Level: 1 (Excellent)      

Study Rundown: Though much literature has been published on vaccine hesitancy in the United States, significantly fewer studies have investigated how to effectively address vaccine hesitancy in the clinical setting. In this article, researchers completed a cluster randomized controlled trial which compared whether or not physician awareness of parental vaccine hesitancy affected the amount of time children of vaccine hesitant parents remained under-immunized. Researchers found that though all parents included in the study were identified as vaccine hesitant from the start, there was no significant difference in under-immunized time amongst those children whose physicians were made aware of their parents’ vaccine hesitancy. Moreover, when completing a per protocol sub-analysis, researchers found that children of vaccine hesitant parents whose providers were made aware of their vaccine hesitant status were actually more likely to have a longer under-immunized time as compared to children of vaccine hesitant parents whose physicians did not know their vaccine hesitancy status. Though the study is limited by the possibly uniqueness of its geographic sampling of families in the pacific northwest, it still reveals an important conclusion, namely that simply making physicians aware of parents who are vaccine hesitant had no impact on increasing vaccine adherence and may even deter patients from immunizing on time. Further research is required into why the phenomenon exists as well as additional methods for combating vaccine hesitancy.

Click here to read the study in Pediatrics

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EvidencePulse™ by 2 Minute Medicine 2026 evidence scan 3 reports You asked top stroke trials 2026 Synthesizing medical evidence... Top 2026 stroke trial results: OCEANIC — ischemic stroke: 6.2% vs 8.4% OPTION* — mRS 0–1: 43.6% vs 34.2% ORIENTAL* — mRS 0–2: 58.6% vs 46.6% *Higher sICH in intervention arms Participants randomizedN OCEANIC 12,327 OPTION 570 ORIENTAL 564 Ask about guidelines or landmark trials... ↑ Try EvidencePulse™ Get the signal. Try it now → Physician-trained medical AI by 2 Minute Medicine

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