Tag: vaccines

1. In this cluster randomized controlled trial, researchers found that informing providers of which parents identified as vaccine hesitant on a standard screening survey had no impact on the length of time the children of these parents remained under-immunized. 2. Researchers also completed a per protocol analysis, studying only parents...

1. In this cluster randomized controlled trial, researchers found that informing providers of which parents identified as vaccine hesitant on a standard screening survey had no impact on the length of time the children of these parents remained under-immunized. 2. Researchers also completed a per protocol analysis, studying only parents...

1. In this national survey, both pediatricians and family physicians (FPs) were more likely to make a strong recommendation for the human papilloma virus (HPV) vaccine in older adolescents as compared to younger adolescents (ages 11 to 12 years). Pediatricians were more likely than FPs to use a presumptive...

Oral live-attenuated polio vaccines (OPV) and injected inactivated polio vaccines IPV) have helped eradicate wild polioviruses. However, there is still a need to develop new vaccines due to risk of outbreaks of vaccine-derived polioviruses. In the process of developing new vaccines, it is important to study the safety of...

1. Pregnant women who received discouraging information about vaccinations, regardless of whether or not they received encouraging information, were more likely to delay vaccination in their infants. 2. Positive, encouraging information about vaccines was not tied to an increase in the timeliness of infant vaccinations. Evidence Rating Level: 2 (Good) Study Rundown:...

1. Maternal vaccination with tetanus toxoid, reduced diphtheria toxoid, acellular pertussis (Tdap) during pregnancy was found to be highly effective in preventing pertussis in newborns during the first year of life. The effect was strongest in the first 2 months of life. 2. Conversely, the cocooning strategy of vaccinating postpartum...

1. The American Academy of Pediatrics (AAP) acknowledges the many benefits of childhood immunization, both direct and indirect. These include herd immunity as a result of high immunization rates, direct protection of the immunized individual, prevention of death and disease epidemics, and cost savings into the billions. 2. The AAP...

1. In this cluster-randomized, open-label trial, a whole-cell cholera vaccine demonstrated moderate effectiveness of around 40% in protecting against severely dehydrating cholera. 2. The vaccine was well tolerated with no reported vaccine-related serious adverse events. Behavioral change had a small augmenting effect to the vaccine efficacy. Evidence Rating Level: 1...

1. Implementation of the rotavirus vaccine schedule was linked with decrease in all-cause gastroenteritis rates. 2. Gastroenteritis hospitalization rates declined similarly in males and females, all race/ethnicity groups, and all ages. Evidence Rating Level: 2 (Good) Study Rundown: Rotavirus is a contagious virus that is the most common cause of...

1. In this combined post-hoc analysis of two phase 3, double-blind randomized trials, the bivalent HPV-16/18 vaccine AS04 was effective and conferred similar levels of protection to women after 3, 2, or 1 doses. Evidence Rating Level: 1 (Excellent) Study Rundown: Prevention against cervical cancer with 3 doses of...