Vaccine protects macaques from the West African Ebola virus [PreClinical]
1. An Ebola vaccine candidate (VSV-EBOV) conferred protection from the 2014/15 West African Ebola virus strain (EBOV-Makona) in macaques when...
1. An Ebola vaccine candidate (VSV-EBOV) conferred protection from the 2014/15 West African Ebola virus strain (EBOV-Makona) in macaques when...
1. On a high-fat diet (HFD), mice genetically predisposed to colorectal cancer (ApcMin mice) developed fewer and smaller tumors when...
1. Mice lacking a gene for syndecan-4 (SDC4), a transmembrane cell receptor, showed less airway inflammation than wild-type (WT) mice...
1. Hematopoietic stem cells (HSCs) were engineered to moderately overexpress platelet-derived growth factor (PDGF-BB), an important bone growth factor. 2....
1. Glucose-responsive vesicles (GRVs), nanoscale polymer spheres loaded with glucose oxidase (GOx) enzyme, released insulin cargo in response to hyperglycemic...
1. Harvesting mouse hematopoietic stem cells (HSCs) in hypoxia (3% oxygen) rather than ambient air (21% oxygen) resulted in greatly...
1. Levels of angiopoietin-like 4 (ANGPTL4), a protein involved in new blood vessel production (angiogenesis), were highly upregulated in various...
1. Treatment with clioquinol (CQ), a small molecule drug that affects zinc regulation, improved social interaction in two mouse models...
1. Depletion of dynamin, a protein involved in maintenance of the actin cytoskeleton, resulted in decreased circulation of large proteins...
1. The small molecule drug birinapant promoted elimination of hepatitis B virus (HBV) in a mouse model of chronic infection....
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