Chronic Disease

Reports of high-impact chronic disease studies by medical professionals

Dabigatran linked to fewer major bleeding events than warfarin in ablation: The RE-CIRCUIT trial

1. The incidence of major bleeding events up to 8 weeks after catheter-directed atrial fibrillation ablation was significantly lower in those receiving continuous therapy...

Price transparency in electronic health records not linked to changes in physician ordering: The...

1. In this randomized controlled trial, electronic health record display of cost for laboratory studies was not linked to a change in clinician ordering...

Mindfulness offers short-term relief from low back pain

1. Mindfulness-based stress reduction may have short-term impact on pain intensity and physical functioning for low back pain patients. 2. Improvements for low back pain...

Direct-acting antiviral therapy for hepatitis C virus associated with hepatitis B virus reactivation in...

1. Patients who have been infected with hepatitis B virus (HBV) and are being treated with direct-acting antiviral agents (DAAs) for hepatitis C virus...

Glucocorticoid compounds improve stem cell transplant efficiency in mice [PreClinical]

  1. Following treatment with glucocorticoids, human hematopoietic stem cells (HSCs) from cord blood demonstrated enhanced homing and engraftment to bone marrow in mice. 2. Glucocorticoids...

Antidepressant use in pregnancy not linked with autism-spectrum disorder in exposed children

1. No significant association between serotonergic antidepressant use and autism spectrum disorder risk was found between exposed and unexposed children. Evidence Rating Level: 2 (Good) Study...

Individualized screening for diabetic retinopathy with fundoscopy and HbA1c

1. Risk of developing clinically significant diabetic retinopathy or macular edema over specified timeframes can be modeled using fundal exam and hemoglobin A1c (HbA1c)...

Mixed cardiovascular benefit with PCSK9 inhibitior bococizumab: The SPIRE trial

1. When added to statin therapy, the proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitor bococizumab significantly reduced the risk of cardiovascular events in patients...

Risankizumab more effective than ustekinumab for moderate-to-severe psoriasis

1. Risankizumab was associated with a significantly greater improvement in the primary endpoint of ≥90% reduction of the Psoriasis Area and Severity Index (PASI)...

Targeted HIV-screening practices more effective for minority youths

1. Based on this prospective cohort study, targeting HIV screening at high-risk youths performed better than the current standard of universal screening. 2. Individuals who...
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