Chronic Disease

Reports of high-impact chronic disease studies by medical professionals

Extensive cancer screening may not improve outcomes for patients with unprovoked venous thromboembolism

1. Although more extensive screening may detect more cases of occult cancer in patients with unprovoked venous thromboembolism (VTE) at the preliminary screening, it...

Candidate drug to prevent HIV infection in women safe and well-tolerated in phase 2...

1. Maraviroc pre-exposure prophylaxis regimens were observed to be safe and well tolerated in patients. 2. No new HIV infections occurred during the course of...

Canagliflozin reduces cardiovascular outcomes in patients with diabetes: The CANVAS

1. Canagliflozin, a sodium glucose cotransporter 2 (SGLT2) inhibitor, significantly reduced the risk of the primary composite outcome of cardiovascular death, nonfatal myocardial infarction,...

Zika virus exposure detected in patients presenting with new neuroinflammatory conditions

1. In this prospective cohort study from Brazil, most patients admitted with new parainfectious/neuroinflammatory conditions including Guillain-Barré syndrome (GBS), meningoencephalitis, or transverse myelitis had...

On the Move exercise program improved mobility in older adults

1. This cluster-randomized, single-blind intervention trial showed that the On the Move exercise program, a program focusing on timing and coordination of movement, was...

Low-dose aspirin reduces incidence of preterm preeclampsia in high-risk pregnancies: The ASPRE trial

1. Low-dose aspirin significantly reduced the incidence of preterm preeclampsia in women identified as high-risk for preeclampsia using a screening protocol that combined maternal...

Little quality evidence on the effectiveness of cannabinoids for treating chronic pain or PTSD

1. There is a paucity of evidence regarding the benefits and harms of plant-based cannabis for posttraumatic stress disorder (PTSD). 2. Currently, it is not...

Sleep duration inversely related to childhood type 2 diabetes risk makers

1. Shorter sleep duration was associated with higher BMI, fat mass index, and insulin levels in children aged 9 to 10 years. 2. Sleep duration...

Limited evidence available to determine effectiveness and safety of cannabis to treat chronic pain

1. There is some evidence that cannabis reduces neuropathic pain, but there is inadequate evidence for other pain types. 2. Possible harms of cannabis use...

Antiretroviral therapy with tenofovir-emtricitabine-efavirenz demonstrates lower rate of adverse birth outcomes than other regimens

1. In an observational study across hospitals in Botswana, women with HIV infection had higher rates of adverse birth outcomes than uninfected women. Women...
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