Chronic Disease

Reports of high-impact chronic disease studies by medical professionals

Fecal immunochemical testing demonstrates good diagnostic accuracy for high-risk individuals

1. Meta-analysis of available studies evaluating the use of fecal immunochemical testing (FIT) for colorectal cancer (CRC) in patients at higher than average personal...

Cetuximab and bevacizumab are similar in combined platin therapy for advanced or metastatic colorectal...

1. In this randomized controlled trial, cetuximab or bevacizumab combined with platin therapy had similar survival rates for patients with KRAS wildtype, advanced, or...

Study reveals suburban clinicians’ perspectives on screening for food insecurity

1. In a mixed methods study of screening for food insecurity (FI) among 6 suburban practices, 3 major themes emerged. 1) time and workflow...

Drug improves cystic fibrosis pulmonary inflammation and protein function [PreClinical]

1. Thymosin α1 (Tα1), an immunomodulatory drug currently in use, decreased lung inflammation in a mouse model of cystic fibrosis (CF). 2. In mice, administration...

Low-cost biochip isolates cells for clinical diagnosis [PreClinical]

1. Researchers manufactured a microfluidic biochip, using an inkjet printing system to apply conductive nanoparticles to a polymer substrate. 2. The biochip used an electric...

Lipid nanoparticles deliver messenger RNA for hemophilia B protein replacement therapy [PreClinical]

1. A lipid nanoparticle (LNP) delivery system was developed to introduce factor IX (FIX) messenger RNA (mRNA) into a FIX deficient mouse model of...

Device thrombosis more likely with bioresorbable scaffolds versus drug-eluting stents

1. Device thrombosis occurred at a higher rate in patients undergoing percutaneous coronary intervention (PCI) utilizing a bioabsorbable scaffold compared to a metallic stent,...

Self-monitoring of glucose in non-insulin dependent diabetics not linked to improved control

1. In this randomized, open-label trial, glucose self-monitoring in patients with non-insulin dependent diabetes mellitus with or without electronic feedback was not associated with...

Inverse relationship between level of education and risk of cardiovascular disease

1. In this prospective cohort study, educational attainment was inversely associated with cardiovascular disease (CVD) risk, in a dose-response relationship. 2. The largest gap in...

HbA1c overestimates mean glucose in black persons compared with whites

1. Mean glucose concentration was significantly lower in black compared to white patients; however, HbA1c levels in black patients were higher than white patients. 2....
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