Endocrinology

Reports of high-impact endocrinology studies by medical professionals

Self-monitoring of glucose in non-insulin dependent diabetics not linked to improved control

1. In this randomized, open-label trial, glucose self-monitoring in patients with non-insulin dependent diabetes mellitus with or without electronic feedback was not associated with...

HbA1c overestimates mean glucose in black persons compared with whites

1. Mean glucose concentration was significantly lower in black compared to white patients; however, HbA1c levels in black patients were higher than white patients. 2....

Metformin linked to decreased BMI z scores in prepubertal children

1. Prepubertal obese children treated with metformin over 6 months had significantly lower BMI z scores compared to those receiving placebo. These differences were...

No link between cesarean delivery and BMI in later childhood

1. Examination of anthopometric data on infants from 2 Danish prospective cohorts showed that infants born by cesarean delivery (CD) vs. vaginal delivery had...

Pravastatin therapy for primary prevention in the elderly did not reduce mortality

1. In this post-hoc analysis of the Lipid-Lowering Trial (LLT) component of the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT-LLT) randomized...

Data support targeted approach to cholesterol screening in young adults

1. In the absence of risk factors, there was low prevalence of increased ASCVD risk in women under 50 and men under 40. 2. Only...

PCSK9 inhibitor significantly reduces the risk of cardiovascular events: The FOURIER trial

1. In addition to significantly lowering levels of low density lipoprotein cholesterol (LDL-C), evolocumab reduced the composite risk of cardiovascular events in atherosclerotic patients...

Alternate-day fasting not superior than calorie restriction in adults

1. Based on this randomized clinical trial, alternate-day fasting did not yield different results with regards to weight loss, blood pressure, or lipid profiles...

Mixed cardiovascular benefit with PCSK9 inhibitior bococizumab: The SPIRE trial

1. When added to statin therapy, the proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitor bococizumab significantly reduced the risk of cardiovascular events in patients...

Significant decline in mortality related to diabetes from 1998 to 2014

1. In a large Swedish registry-cohort study, the authors report significant declines in all-cause mortality and diabetes-related complications in patients with both type 1...
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