Endocrinology

Reports of high-impact endocrinology studies by medical professionals

Evolocumab demonstrated to have long-term efficacy at lowering low-density lipoprotiein: The Osler-1 trial

1. This multi-year, open-label extension of phase 2 trials examining the LDL-lowering efficacy of evolocumab (PCSK9-inhibitor) showed that evolocumab plus standard of care lipid...

Suboptimal dietary habits linked to deaths from heart disease, stroke, and type 2 diabetes

1. Over 45% of deaths due to heart disease, stroke, and type 2 diabetes in US adults in 2012 was due to suboptimal dietary...

Thiazolidinediones linked to regression of fibrosis in non-alcoholic steatohepatitis

1. Based on this meta-analysis of available randomized controlled trials (RCTs), use of thiazolidinediones in patients with non-alcoholic steatohepatitis (NASH) demonstrated regression of liver...

Reminder devices may not improve medication adherence: The REMIND trial

1. In this randomized controlled trial, three low-cost reminder devices (pill bottle strip with toggles, digital timer cap, or standard pillbox) did not significantly...

Adolescents with type II diabetes have more complications than those with type I

1. In this prospective cohort, adolescents with type II diabetes (DM2) were more predisposed to almost every diabetes related complication at age 21 than...

 Transgender adolescents report less sexual activity than non-transgender peers

1. Dutch transgender youths ages 12-17 reported fewer sexual and romantic experiences than peers in the general population. 2. Gender differences were seen between transgirls...

Tighter glucose control does not decrease ICU-free days in critically ill pediatric patients: The...

1. The study demonstrated that in critically ill pediatric patients, there was no significant difference in total number of ICU-free days up to day...

Testosterone replacement may improve anemia in older men with low testosterone

1. In this non-randomized, double-blind, placebo-controlled study, men 65 years or older who had unexplained anemia with low serum testosterone had an increase in...

Testosterone administration may increase bone mineral density in older men with low testosterone

1. This placebo-controlled, double-blind trial showed that in older men (³65 years old) with low measured testosterone, one year of testosterone administration increased volumetric...

Maintenance program associated with reduced weight regain after weight loss

1. After 56 weeks of a weight maintenance intervention program, researchers found that mean weight regain in the intervention group (0.75 kg) was lower...
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