Pulmonology

Reports of high-impact pulmonology studies by medical professionals

AKI associated with increased mortality among critically ill children and young adults: The AWARE...

1. The study demonstrated that acute kidney injury (AKI) is common in critically ill children and young adults, and is associated with increased mortality. 2....

Noninvasive respiratory support, methylxanthines among interventions that reduce re-intubations in preterm infants

1. In a meta-analysis of randomized studies evaluating efforts to reduce re-intubations and respiratory failure in preterm infants, non-invasive respiratory support and use of...

Low-intensity smoking associated with increased mortality

1. In this prospective cohort study, individuals who consistently smoked fewer than 1 or 1 to 10 cigarettes per day had increased risk of...

Pembrolizumab associated improved survival for NSCLC compared to platinum-based chemotherapy

1. Progression free survival and overall survival was significantly increased in patients who received pembrolizumab vs. patients who received platinum-based chemotherapy. 2. Treatment related toxicities...

Blocking fatty acid synthesis may curb lung cancer growth [PreClinical]

1. ND-646, a small molecule inhibitor of FASyn, an enzyme involved in fatty acid synthesis, caused reduced growth and viability of non-small cell lung cancer...

Levosimendan does not improve sepsis-related outcomes: The LeoPARDS trial

1. No significant difference was observed in 28-day mean SOFA score or overall mortality in patients who received levosimendan vs. controls. 2. A significant increase...

Long-term oxygen not linked with improved mortality in moderate COPD: The LOTT trial

1. There was no mortality benefit associated with receiving long-term oxygen supplementation in patients with stable chronic obstructive pulmonary disease (COPD) and resting or...

Tobacco-related cancer deaths in the US disproportionately affects Southern states

1. Based on US prospective studies and state-specific smoking prevalence data, about 29% of all cancer deaths in 2014 were attributable to cigarette smoking. 2....

Antenatal steroids improved outcomes in a dose-dependent manner in extremely premature infants

1. Based on this prospective cohort study, use of antenatal steroids (ANS) was linked to improved mortality and neurologic outcomes, and lower rates of...

The effects of viral respiratory tract infections on neonatal care

1. Amongst infants in the neonatal intensive care unit (NICU) with viral respiratory tract infections (VRTIs), 51% required additional respiratory support. 2. When compared to...
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