• About
  • Masthead
  • License Content
  • Advertise
  • Submit Press Release
  • RSS/Email List
  • Write for us
  • Contact us
2 Minute Medicine
No Result
View All Result

No products in the cart.

SUBSCRIBE
  • Specialties
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • The Scan
  • Wellness
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • AccountLog-in/out
    • Subscribe
    • Sign-in
    • My account
2 Minute Medicine
  • Specialties
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • The Scan
  • Wellness
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • AccountLog-in/out
    • Subscribe
    • Sign-in
    • My account
SUBSCRIBE
2 Minute Medicine
Subscribe
Home Weekly Rewinds

2 Minute Medicine Rewind June 13, 2016

byDavid Ouyang
July 2, 2016
in Weekly Rewinds
Reading Time: 3 mins read
0
Share on FacebookShare on Twitter

Cryoballoon or Radiofrequency Ablation for Paroxysmal Atrial Fibrillation

Pulmonary vein isolation is often attempted as an interventional approach for drug-refractory paroxysmal atrial fibrillation to prevent conduction from aberrant foci of ectopy near the pulmonary veins. Both radiofrequency ablation by catheter as well as cryoballoon ablation approaches are in use. In this multicenter, randomized trial of 762 patients with drug-resistant paroxysmal atrial fibrillation, study participants were randomized to either radiofrequency ablation or cryoballoon ablation and followed for a mean duration of 1.5 years for subsequent recurrence, use of antiarrhythmic drugs, or repeat ablation. In this study, the 1 year Kaplan-Meier clinical failure rate was 34.6% in the cryoballoon group vs. 35.9% in the radiofrequency group (p < 0.001 for inferiority). By one year, there was also similar rates of a composite of death, cerebrovascular events, or severe procedure-related complications (10.2% vs. 12.8%, p = 0.24). In this study, there was no difference in safety or efficacy between cryoballoon and radiofrequency ablation for paroxysmal atrial fibrillation.

Trends in Obesity Among Adults in the United States, 2005 to 2014

Over the last 30 years, there has been an increased prevalence of obesity in the United States documented as early as 1980. The National Health and Nutrition Examination Survey (NHANES) continues to be administered annually to identify trends in national disease prevalence. In this report of NHANES survey results from 2013-2015, 2638 men and 2817 women were surveyed on health and demographics including race, smoking status, and education. In this nationally representative survey, the age-adjusted prevalence of obesity was 37.7% (95% CI: 35.8 to 39.7%) for men and 35.0% (95% CI; 32.8% to 37.3%) for women. Compared to surveys prior to 2005, there are significant increasing linear trends among women (p = 0.004) but not among men ( p = 0.30) for overall obesity. The prevalence of obesity remains high in the United States and appears to be rising for women.

Characteristics and Outcomes of Patients Presenting With Hypertensive Urgency in the Office Setting

The complications of chronic hypertension are well established, as are the risks brief episodes of severe hypertension. However, the short-term outcomes of hypertensive urgency (asymptomatic systolic blood pressures greater than 180mmHg or diastolic blood pressures greater than 110mmHg) are unknown and there is significant practice variation between hospital admission or outpatient management. In this retrospective cohort study of patients seen in outpatient clinic in the Cleveland Clinic Healthcare system, 58,535 patients met blood pressure criteria for hypertensive urgency. In propensity-matched analysis, the outcomes of 852 patients sent home were compared with 426 patients admitted to the hospital for hypertensive urgency. There was no significant difference in major adverse cardiovascular events up to 6 months (0.9% vs. 0.9%, p > 0.99), however patients sent home were more likely to have uncontrolled hypertension at 1 month (86.3% vs. 81.9%, p = 0.04). Patients who were initially admitted were more likely to be readmitted up to 30 days after initial office visit (11.3% vs. 6.9%, p = 0.009). Despite significant practice variation, there was not much difference in major adverse cardiovascular events up to 6 months afterwards, however most patients still had uncontrolled hypertension in subsequent follow-up.

Risk Factors and Outcomes for Patients With Follicular Lymphoma Who Had Histologic Transformation After Response to First-Line Immunochemotherapy in the PRIMA Trial

RELATED REPORTS

Abnormal menstruation may be associated with worse cardiometabolic outcomes later in life

Past infection with pre-omicron variants of COVID-19 protects against re-infection

No difference in complete expulsion of intrauterine device between early and standard interval postpartum placement

Histologic transformation of low grade follicular lymphoma often results in aggressive, treatment resistant diffuse large B-cell lymphoma. There are few studies of patients who have transformed follicular lymphoma who previously responded to immunotherapy. In the PRIMA trial, 1,018 patients with follicular lymphoma were followed for a median of 6 years and disease progression was observed in 463 (45.5%) patients. Of these patients, 37% of biopsies during the first year of follow-up showed histologic transformation. Response to immunotherapy or rituximab had no impact on the risk of histologic transformation, however of patients who previously responded to immunotherapy but had histological transformation, there was statistically significantly more disease progression after salvage chemotherapy (28.2 vs. 9.6%, p < 0.001). Overall survival was worse (3.8 vs. 6.4 years, HR 3.9) for patients with histological transformation. The authors suggest that histological transformation in patients with follicular lymphoma that previously responded to immunotherapy is associated with poor outcomes that might be best served with aggressive salvage chemotherapy and/or autologous stem cell transplantation.

Image: PD

©2016 2 Minute Medicine, Inc. All rights reserved. No works may be reproduced without expressed written consent from 2 Minute Medicine, Inc. Inquire about licensing here. No article should be construed as medical advice and is not intended as such by the authors or by 2 Minute Medicine, Inc.

Previous Post

Neutralizing antibodies protect against SHIV infection in young macaques [PreClinical]

Next Post

Low-cost test rapidly detects Zika virus [PreClinical]

RelatedReports

Cardiology

Abnormal menstruation may be associated with worse cardiometabolic outcomes later in life

March 28, 2023
Decreased expression of nasal ACE2 may be correlated with lower prevalence of COVID-19 in children
Chronic Disease

Past infection with pre-omicron variants of COVID-19 protects against re-infection

March 28, 2023
Lower long-term IUD use among young women
Obstetrics

No difference in complete expulsion of intrauterine device between early and standard interval postpartum placement

March 28, 2023
Nivolumab may be effective in platinum-resistant ovarian cancer
Obstetrics

Immediate postpartum opioid administration not associated with adverse infant outcomes

March 28, 2023
Next Post
Nanoparticle delivery of aurora kinase inhibitor may improve tumor treatment [PreClinical]

Low-cost test rapidly detects Zika virus [PreClinical]

HOSPITAL score predicts risk of 30-day potentially avoidable readmission to hospital

Opioid prescriptions common after hospital discharge

Digital imaging detects sight-threatening retinopathy of prematurity

Tenofovir treatment associated with reduced perinatal transmission of hepatitis B virus

License Our Award-Winning Physician-Written Medical News and Visual Abstracts

2 Minute Medicine is the leading authoritative medical news licensing service, and the only with reports written by practicing doctors.

LICENSE CONTENT

2MM+ Premium Access

No ads & unlimited access to all current reports, over 9000 searchable archived reports, visual abstracts, Weekly Rewinds, and the online edition of The Classics Series™ textbook.

Subscription Options
2 Minute Medicine

2 Minute Medicine® is an award winning, physician-run, expert medical media company. Our content is curated, written and edited by practicing health professionals who have clinical and scientific expertise in their field of reporting. Our editorial management team is comprised of highly-trained MD physicians. Join numerous brands, companies, and hospitals who trust our licensed content.

Recent Reports

  • Abnormal menstruation may be associated with worse cardiometabolic outcomes later in life
  • Past infection with pre-omicron variants of COVID-19 protects against re-infection
  • No difference in complete expulsion of intrauterine device between early and standard interval postpartum placement
License Content
Terms of Use | Disclaimer
Cookie Policy
Privacy Statement (EU)
Disclaimer

© 2021 2 Minute Medicine, Inc. - Physician-written medical news.

  • Specialties
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • The Scan
  • Wellness
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • Account
    • Subscribe
    • Sign-in
    • My account

© 2021 2 Minute Medicine, Inc. - Physician-written medical news.

Want more physician-written
medical news?

Join over 10 million yearly readers and numerous companies. For healthcare professionals
and the public.

Subscribe for free today!

Subscription options