• About
  • Masthead
  • License Content
  • Advertise
  • Press Releases
  • Newsroom
  • RSS/Email List
  • 2MM Podcast
  • Write for us
  • Contact Us
2 Minute Medicine
No Result
View All Result

No products in the cart.

Sign in
SUBSCRIBE
  • About
  • Specialties
    • All Specialties, All Recent Reports
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Pharma
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
    • Rewinds
    • The Scan
  • EvidencePulse™
  • HypeCheck™
  • AI News
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Tools
    • NPI Registry Lookup
    • RVU Search
  • Partners
    • License Content
    • Advertise with Us
2 Minute Medicine
  • About
  • Specialties
    • All Specialties, All Recent Reports
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Pharma
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
    • Rewinds
    • The Scan
  • EvidencePulse™
  • HypeCheck™
  • AI News
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Tools
    • NPI Registry Lookup
    • RVU Search
  • Partners
    • License Content
    • Advertise with Us
Sign in
SUBSCRIBE
2 Minute Medicine
Sign in
Subscribe
2 Minute MedicineFree on Google PlayGet
✦ EvidencePulse™ by 2 Minute Medicine 2026 evidence scan 3 reports You asked top stroke trials 2026 Synthesizing medical evidence... Top 2026 stroke trial results: OCEANIC — ischemic stroke: 6.2% vs 8.4% OPTION* — mRS 0–1: 43.6% vs 34.2% ORIENTAL* — mRS 0–2: 58.6% vs 46.6% *Higher sICH in intervention arms Participants randomizedN OCEANIC 12,327 OPTION 570 ORIENTAL 564 Ask about guidelines or landmark trials... ↑ Try EvidencePulse™ Ask the evidence.
Get the signal.
Try it now → Physician-trained medical AI by 2 Minute Medicine
Home All Specialties Chronic Disease

Volumetric diet and time-restricted eating demonstrate similar outcomes for weight reduction

byJayden BerdugoandAlex Chan
June 24, 2025
in Chronic Disease, Endocrinology, Gastroenterology
Reading Time: 2 mins read
Increasing maternal BMI linked to higher risk of cerebral palsy
Share on FacebookShare on TwitterShare on LinkedIn

1. In this randomized controlled trial comparing the volumetrics diet (VD) and time-restricted eating (TRE), both interventions led to significant reductions in body weight, body mass index, and fat mass, while preserving lean body mass. 

2. VD had a significantly lower adherence rate compared with TRE. 

Evidence Rating Level: 1 (Excellent) 

Obesity has been a global issue in recent decades, with increased prevalence of cardiovascular disease as well as other economic consequences. To avoid these issues, which tend to cement in later life, early intervention in maintaining body weight (BW), fat mass (FM), and skeletal muscle mass (SMM) has been proposed. In weight loss, the primary driver is caloric deficit; however, this can lead to protein shortages impacting SMM preservation and must be done sustainably. Two diets shown to be effective for reducing BW and FM are time-restricted eating (TRE), which limits the daily eating window, and the volumetric diet (VD), which emphasizes consuming large volumes of nutrient-dense low-calorie foods to promote satiety. This study examined the effects of these diets on normal and high-weight individuals who maintained their higher levels of physical activity throughout the diet adherence on their body composition. This randomized controlled trial was conducted over 12 weeks and examined body weight (BW), relative and absolute fat mass (FM), lean body mass (LBM), body mass index (BMI), waist circumference (WC), and hip circumference (HC). After meeting eligibility, a total of 37 participants were included in the study, with 21 in the VD group and 16 in the TRE group. Both groups had a significant decrease in BW (p=0.0002; d=0.61), relative FM (p<0.0001; d=0.84), absolute FM (p<0.0001; d=0.85), BMI (p=0.0001; d=0.60), WC (p<0.0001; d=0.92), HC (p=0.003; d=0.51), and WHR (p<0.001; d=0.90) with no significant difference between the groups. According to the questionnaires, both groups experienced a nonsignificant decline in adherence; however, between the groups, there was a significantly higher adherence rate for TRE (5.78 ± 1.13 days per week) compared to VD (5.29 ± 1.49 days per week) (p = 0.0002; d = 0.362). These findings suggest that both interventions are effective in counteracting age-related increases in fat mass, with TRE emerging as a potentially more sustainable option due to the higher adherence rates. 

Click to read the study in Nutrition Journal

Image: PD

RELATED REPORTS

Zanidatamab-hrii combinations improved survival in first-line HER2-positive advanced gastroesophageal adenocarcinoma

Upacicalcet reduced parathyroid hormone in hemodialysis patients with secondary hyperparathyroidism in PATH-1 and PATH-2

©2025 2 Minute Medicine, Inc. All rights reserved. No works may be reproduced without expressed written consent from 2 Minute Medicine, Inc. Inquire about licensing here. No article should be construed as medical advice and is not intended as such by the authors or by 2 Minute Medicine, Inc.

Previous Post

Tirzepatide-associated improvements in cardiometabolic risk factors linked to degree of weight loss

Next Post

Abbreviated MRI is superior to whole-breast ultrasound for detection of cancer in dense breasts

RelatedReports

A sleeping patient in a hospital bed with an IV drip, a clock showing time, and light shining from a lamp, suggesting themes of sleep, time, and chemotherapy treatment.
2MM Trial Briefs

Zanidatamab-hrii combinations improved survival in first-line HER2-positive advanced gastroesophageal adenocarcinoma

October 27, 2026
A patient undergoing dialysis while using a pedaling device for exercise.
2MM Trial Briefs

Upacicalcet reduced parathyroid hormone in hemodialysis patients with secondary hyperparathyroidism in PATH-1 and PATH-2

October 27, 2026
An envelope is being held with a calendar and an illustration of the colon in the background, indicating a reminder for colorectal screening.
2MM Trial Briefs

WGS Oncodetect showed higher recurrence sensitivity than WES Oncodetect in colorectal cancer

October 26, 2026
An incubator for preterm infants, alongside monitoring equipment and oxygen delivery components.
Gastroenterology

Stool biomarkers may be effective in the evaluation of necrotizing enterocolitis in preterm infants

October 26, 2026
Next Post

Abbreviated MRI is superior to whole-breast ultrasound for detection of cancer in dense breasts

Biosimilar to infliximab shows equivalent safety and efficacy for treating Crohn’s disease

Food compounds associated with disease activity in inflammatory bowel disease 

PCI not superior to medical therapy alone in stable coronary disease: The COURAGE study

Novel inhibitory antibody, MAR001, lowers triglycerides and remnant cholesterol in humans

✦ EvidencePulse™ by 2 Minute Medicine 2026 evidence scan 3 reports You asked top stroke trials 2026 Synthesizing medical evidence... Top 2026 stroke trial results: OCEANIC — ischemic stroke: 6.2% vs 8.4% OPTION* — mRS 0–1: 43.6% vs 34.2% ORIENTAL* — mRS 0–2: 58.6% vs 46.6% *Higher sICH in intervention arms Participants randomizedN OCEANIC 12,327 OPTION 570 ORIENTAL 564 Ask about guidelines or landmark trials... Try EvidencePulse™ Get the signal. Try it now → Physician-trained medical AI by 2 Minute Medicine

2MM+ All Access

Full details →
$4.99 /month

3-day free trial · cancel anytime

  • ✓100+ physician-written reports
  • ✓EvidencePulse™ + HypeCheck™
  • ✓Ad-free reading + newsletters
Start 3-day free trial

Then $4.99/month. Manage renewal in your account.

NPI Lookup · Free

Look up any US clinician

Search by name or NPI number, live from the CMS NPI Registry.

  • OIG exclusion check
  • Licenses and specialties
  • No account needed
Open NPI Lookup →

2 Minute Medicine® is an award winning, physician-run, expert medical media company. Our content is curated, written and edited by practicing health professionals who have clinical and scientific expertise in their field of reporting. Our editorial management team is comprised of highly-trained MD physicians. Join numerous brands, companies, and hospitals who trust our licensed content.

Recent Reports

  • Zanidatamab-hrii combinations improved survival in first-line HER2-positive advanced gastroesophageal adenocarcinoma
  • Upacicalcet reduced parathyroid hormone in hemodialysis patients with secondary hyperparathyroidism in PATH-1 and PATH-2
  • WGS Oncodetect showed higher recurrence sensitivity than WES Oncodetect in colorectal cancer
License Content
Terms of Use | Disclaimer
Cookie Policy

Get the app

Read 2 Minute Medicine on iPhone, iPad and Android.

Download on the App StoreGet it on Google Play
QR code for www.2minutemedicine.com/app
On a computer? Scan this with your phone’s camera.
2MM+ All Access Full details →

The medical literature, distilled daily.

Monthly plan selected: $4.99 /month.

$4.99/month

3-day free trial · cancel anytime

Start 3-day free trial

Then $4.99/month. Manage renewal in your account.

Yearly plan selected: $49.90 /year.

$49.90/year

2 months free

Start 3-day free trial

Then $49.90/year.

Membership benefits

  • ✓100+ physician-written reports
  • ✓AI EvidencePulse™ + HypeCheck™
  • ✓Ad-free reading + newsletters
  • ✓NPI watchlist + bulk NPI verification

Already a member? Sign in

  • Get the app
  • About
  • Specialties
    • All Specialties, All Recent Reports
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Pharma
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
    • Rewinds
    • The Scan
  • EvidencePulse™
  • HypeCheck™
  • AI News
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Tools
    • NPI Registry Lookup
    • RVU Search
  • Partners
    • License Content
    • Advertise with Us
No Result
View All Result

© 2026 2 Minute Medicine, Inc. - Physician-written medical news.