• About
  • Masthead
  • License Content
  • Advertise
  • Submit Press Release
  • RSS/Email List
  • 2MM Podcast
  • Write for us
  • Contact Us
2 Minute Medicine
No Result
View All Result

No products in the cart.

SUBSCRIBE
  • Specialties
    • All Specialties, All Recent Reports
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Pharma
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • AI Roundup
  • Pharma
  • The Scan+
  • Classics™+
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Podcasts
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • Account
    • Subscribe
    • Sign-in
    • My account
2 Minute Medicine
  • Specialties
    • All Specialties, All Recent Reports
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Pharma
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • AI Roundup
  • Pharma
  • The Scan+
  • Classics™+
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Podcasts
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • Account
    • Subscribe
    • Sign-in
    • My account
SUBSCRIBE
2 Minute Medicine
Subscribe
Home All Specialties Infectious Disease

Among sepsis survivors, primary care interventions not associated with improved mental health outcomes

byMilana Bogorodskaya, MDandAnees Daud
June 29, 2016
in Infectious Disease, Psychiatry, Pulmonology
Reading Time: 3 mins read
0
Share on FacebookShare on Twitter

1. Compared to standard care, 6 months of primary care interventions were not associated with any improvement in mental health-related quality of life (QoL) among survivors of sepsis.

2. At 6 months of follow up, patients receiving primary care interventions reported improved physical functioning and an increased ability to perform activities of daily living (ADL).

Evidence Rating Level: 1 (Excellent)

Study Rundown: Sepsis, a severe systemic inflammatory response triggered by an infection, is a common entity requiring care in the intensive care unit (ICU). As mortality from sepsis decreases, the morbidities associated with post-sepsis survival present a rising concern. However, little is known about the optimal outpatient management of sepsis survivors. This study sought to determine whether a primary care-based intervention based on actively following and addressing patient’s post-sepsis concerns would lead to improved mental health-related QoL. After 6 months of intervention, the study found that patients receiving primary care interventions did not have significantly better mental health-related QoL compared to those receiving standard care, although they did report improvements in physical functioning and performance of ADLs.

This is the first large-scale randomized, controlled trial that sought to improve outcomes in sepsis survivors post hospital discharge. Though the study was well-designed, and benefited by utilizing previously incorporated PCP relationships, it was limited in a few ways. Most concerning for the reliability of the results, 22.7% of all patients were lost to follow up, and only 70.3% of patients in the intervention group received the planned therapy. Nevertheless, this study demonstrates that comprehensive follow up care for sepsis survivors may improve their physical functioning and further research is needed to identify the interventions most effective in improving long-term QoL.

Click to read the study, published today in JAMA

RELATED REPORTS

The Scan by 2 Minute Medicine®: Celebrity diagnoses spur screenings, athlete mental-health push, reality-TV heart lesson, and a sitcom PSA wave

Early acetaminophen use reduces mortality risk in patients with sepsis-associated encephalopathy

Intravenous hydrocortisone may reduce risk of kidney failure in patients with sepsis

Relevant Reading: Long-term mortality and quality of life in sepsis: a systematic review.

In-Depth [randomized controlled trial]: This randomized, controlled trial was conducted in Germany and assigned 148 patients to receive comprehensive primary care-based post-sepsis therapy and 143 patients to receive usual primary care without additional monitoring. The tested intervention specifically consisted of a post-sepsis information packet, specialty services contacts, and frequent follow up by a case manager for symptom monitoring and management. Patients received 6 months of their assigned intervention and were followed for 12 months in total. The primary outcome assessed in this study was the change in mental health-related QoL 6 months after discharge from the ICU, as assessed by the SF-36 questionnaire. At baseline, patients in both groups had mental health-related QoL levels similar to the population as a whole—depressive symptoms were present in 24.2% of participants and PTSD symptoms in 19.6%. There was no significant difference in the primary outcome at 6 months (mean change MCS score 3.79 vs. 1.64, p = 0.28). However, the intervention group demonstrated improved physical functioning (mean XSDMA-F score 38 vs. 46.9; p = 0.04), less physical disability (mean XSFMA-B score 42.5 vs. 52.4; p = 0.03), and fewer ADL impairments (mean 8.6 vs. 7.6; p = 0.03) than the control group at 6 months.

Image: CC/Wiki

©2016 2 Minute Medicine, Inc. All rights reserved. No works may be reproduced without expressed written consent from 2 Minute Medicine, Inc. Inquire about licensing here. No article should be construed as medical advice and is not intended as such by the authors or by 2 Minute Medicine, Inc.

Tags: intensive caremental healthsepsis
Previous Post

Omega-3 polyunsaturated fatty acids linked to lower mortality from coronary heart disease

Next Post

Rehabilitation beneficial for patients with respiratory failure

RelatedReports

The Scan by 2 Minute Medicine®:  Ultra-Trail du Mont-Blanc, Taylor Swift, NBA rookie Chet Holmgren and Magic Mushrooms!
The Scan by 2 Minute Medicine®

The Scan by 2 Minute Medicine®: Celebrity diagnoses spur screenings, athlete mental-health push, reality-TV heart lesson, and a sitcom PSA wave

July 2, 2025
Emergency

Early acetaminophen use reduces mortality risk in patients with sepsis-associated encephalopathy

July 1, 2025
Being overweight and obese associated with increased incidence of chronic kidney disease
Emergency

Intravenous hydrocortisone may reduce risk of kidney failure in patients with sepsis

June 5, 2025
Parents often unaware of adolescents’ suicidal thoughts
AI Roundup

Mental Health Chatbot Woebot Shown to Help with Postpartum Depression and Anxiety

May 13, 2025
Next Post
Reduced gestational weight gain with lifestyle intervention

Rehabilitation beneficial for patients with respiratory failure

ACE-inhibitor use associated with decreased conduction system disease

ACE-inhibitor use associated with decreased conduction system disease

RTS,SA/S01 anti-malarial vaccine efficacy wanes significantly over time

RTS,SA/S01 anti-malarial vaccine efficacy wanes significantly over time

2 Minute Medicine® is an award winning, physician-run, expert medical media company. Our content is curated, written and edited by practicing health professionals who have clinical and scientific expertise in their field of reporting. Our editorial management team is comprised of highly-trained MD physicians. Join numerous brands, companies, and hospitals who trust our licensed content.

Recent Reports

  • Structured exercise intervention improves survival in colon cancer patients
  • #VisualAbstract: Neoadjuvant and Adjuvant Pembrolizumab in Locally Advanced Head and Neck Cancer
  • Cerebral embolic protection does not decrease stroke incidence in TAVI patients
License Content
Terms of Use | Disclaimer
Cookie Policy
Privacy Statement (EU)
Disclaimer

© 2021 2 Minute Medicine, Inc. - Physician-written medical news.

  • Specialties
    • All Specialties, All Recent Reports
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Pharma
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • AI Roundup
  • Pharma
  • The Scan
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Podcasts
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • Account
    • Subscribe
    • Sign-in
    • My account
No Result
View All Result

© 2021 2 Minute Medicine, Inc. - Physician-written medical news.