2 Minute Medicine Rewind July 6, 2026
Efficacy of leflunomide in active Takayasu arteritis: a randomized double-blind placebo-controlled trial subtitle: Takayasu arteritis clinical trial in China (TACTIC) ...
Tag: sepsis
Use of procalcitonin in neonatal late-onset sepsis may reduce the duration of antibiotic therapy without increase in mortality
1. Incorporating procalcitonin-guided decision making in the management of neonatal late-onset sepsis significantly reduced the duration of antibiotic treatment without ...
2 Minute Medicine Rewind May 25, 2026
Validation of 2 Syncope Risk Scores and Comparison With Physician Risk Estimation 1. The Canadian Syncope Risk Score (CSRS) and ...
Fluoxetine may improve hemodynamic status and organ dysfunction in patients with severe sepsis
1. Adjunctive fluoxetine significantly reduced vasopressor duration and ICU length of stay in patients with severe sepsis. 2. Fluoxetine improved ...
![Adverse pregnancy outcomes associated with thrombophilias [Classics Series]](https://www.2minutemedicine.com/wp-content/uploads/2015/07/Classics-2-Minute-Medicine-e1436017941513-350x250.png)
SOAP II Trial: Shaping Vasopressor Choice in Septic Shock
Why SOAP II Remains Important Septic shock requires timely resuscitation, and vasopressor selection is a critical piece of management. The ...
Neutrophil-to-lymphocyte ratio may be a useful marker of mortality in septic patients with liver cirrhosis
1. In septic patients with liver cirrhosis, the neutrophil-to-lymphocyte (NLR) ratio was positively correlated with all-cause mortality. Evidence Rating Level: ...
Red cell distribution width to albumin ratio may be a useful prognostic marker in the critical care setting
1. Higher red cell distribution width to albumin ratio (RAR) values were associated nonlinearly with a higher mortality risk. 2. ...
Early acetaminophen use reduces mortality risk in patients with sepsis-associated encephalopathy
1. Administration of acetaminophen within 48h of intensive care unit admission was associated with reduced short- and long-term mortality in ...
Intravenous hydrocortisone may reduce risk of kidney failure in patients with sepsis
1. Intravenous hydrocortisone treatment was associated with reduced odds of new kidney replacement in patients with septic shock. Evidence Rating ...
SEP-1 sepsis management bundle not associated with improved mortality
1. In this systematic review, there was minimal evidence of improved sepsis mortality with implementation of the Severe Sepsis and ...
