No advantage of continuous vs intermittent meropenem in critically ill patients – the MERCY trial
1. The MERCY trial revealed that continuous infusion of meropenem does not confer a significant advantage over intermittent administration in ...
Tag: sepsis
Shorter antibiotic therapy courses likely noninferior in the treatment of complicated urinary tract infections and bacteremia
1. In bacteremic patients with complicated UTI, a 10-day course of typical antibiotics or a 7-day course of IV beta-lactams ...
Higher mean arterial pressure targets may be preferable for patients with sepsis
1. In this retrospective cohort study, patients with sepsis and high-mean arterial pressure (MAP) management had a significantly lower 30-, ...
Early restrictive fluid management does not reduce mortality in sepsis-induced hypotension
1. Early use of vasopressors combined with a conservative fluid resuscitation did not result in a mortality benefit over a ...
Balanced intravenous solutions reduce risk of hyperchloremia in the pediatric intensive care unit
1. In a randomized controlled trial of critically ill pediatric patients requiring intravenous fluid therapy, children receiving saline were significantly ...
#VisualAbstract: Restriction of Intravenous Fluids in ICU Patients with Septic Shock
Click to read this study in the New England Journal of Medicine.
#VisualAbstract: Intravenous vitamin C increases mortality and organ dysfunction in sepsis patients
1. In patients with sepsis receiving a vasopressor in the intensive care unit (ICU), intravenous vitamin C was associated with ...
Intravenous fluid restriction does not improve septic shock outcomes
1. There was no significant difference in mortality among septic shock patients in the intensive care unit (ICU) between standard ...
Intravenous vitamin C increases mortality and organ dysfunction in sepsis patients
1. In patients with sepsis receiving a vasopressor in the intensive care unit (ICU), intravenous vitamin C was associated with ...