Tag: intensive care

1. Hydroxychloroquine use in hospitalized and tocilizumab use in ICU lab-positive COVID-19 patients were not been associated with decreased death. Evidence Rating Level: 2 (Good) There is ongoing research into evaluating potential treatment options for COVID-19. Despite conflicting evidence, hydroxychloroquine (with or without azithromycin) remains a popular option, while  preliminary results...
1. In this case series, SARS-CoV-2 infection in children leading to multisystem inflammatory syndrome often required intensive care. 2. Of those who required intensive care, many required vasoactive support and inflammatory biomarkers were elevated in almost all patients. Evidence Rating Level: 3 (Average) Study Rundown: Coronavirus disease 2019 (COVID-19) has strained the...
1. The 3 Wishes Project (3WP), which strives to provide humanistic care and honor the dignity of end-of-life (EOL) patients, was shown to be valuable, transferable, affordable, and sustainable at one year follow-up. 2. In addition to patients and families, hospital staff also benefited from the program through improved camaraderie...
1. Infants ≥ 34 weeks’ gestational age (GA) comprised 75% of the median proportions of neonatal intensive care unit (NICU) admissions across level II-IV NICUs, and only 15% of this group were considered to be high acuity. Evidence Rating Level: 4 (Below Average) Study Rundown: A recent increase in NICU...
1. Among deaths at one, large children’s hospital, the most common mode of inpatient death was withdrawal of life sustaining technologies, followed by nonescalation of care during or at the time of death, and failed resuscitation (code). 2. Older children, neonates, and children with malignancies were significantly more likely to...
1. Family-support intervention delivered by an interprofessional intensive care unit (ICU) team did not significantly reduce anxiety and depression among surrogates of critically ill patients. 2. Surrogates and families in the family-support intervention group were more likely to report improved clinician-family communication and better patient-centered care, and also had a...
1. Extracorporeal membrane oxygenation (ECMO) for severe acute respiratory distress syndrome (ARDS) did not show a 60-day mortality benefit compared to conventional ventilation and ECMO rescue therapy. 2. There were more adverse events in the ECMO group with respect to bleeding requiring transfusion and severe thrombocytopenia. Evidence Rating Level: 1 (Excellent)      Study...
1. The most commonly reported parental hopes for critically ill children fell within the domains of quality of life, concerns regarding physical body, future well-being, and length of life. 2. Over a 20-month time period, domains showing the largest increases in parental hope reports included quality of life, future...
1. Patients with septic shock in the intensive care unit (ICU) undergoing mechanical ventilation receiving hydrocortisone plus fludrocortisone had a lower 90-day all-cause mortality compared to placebo treated patients. 2. The mortality rate at ICU and hospital discharge, and day 180 were significantly lower in the hydrocortisone plus fludrocortisone group,...
1. Use of balanced crystalloids (lactated Ringers or Plasma-Lyte A) was associated with a significant reduction in acute kidney injury events compared to normal saline among intensive care unit (ICU) patients. 2. Use of balanced crystalloids was also associated with lower though nonsignificant in-hospital mortality at 30-days after admission. Evidence Rating...