Limited evidence of utility and risks of multi-cancer detection tests for screening
1. In this systematic review, no studies were found that assessed the benefits of multi-cancer detection tests for cancer screening....
Semaglutide and tirzepatide may be cost-effective for knee osteoarthritis in patients with obesity
1. In this microsimulation model, the two glucagon-like peptide-1 receptor agonists were shown to be cost-effective when added to usual...
Ending Ryan White services may increase human immunodeficiency virus incidence
1. In this simulation study involving persons with human immunodeficiency virus living in the United States, ending Ryan White services...
Pre-conception computed tomography ionizing radiation may be associated with worse reproductive outcomes
1. In this population-based cohort study, women who had received at least one computer tomography scan prior to conception had...
Personalized risk messages may not increase colorectal cancer screening uptake
1. In this randomized controlled trial, using personalized risk messages and provider notifications did not significantly increase screening uptake overall....
Utility of long-term routine laboratory toxicity monitoring of immunomodulatory drugs in rheumatoid arthritis
1. In this retrospective cohort study involving patients with rheumatoid arthritis on disease-modifying antirheumatic drugs, long-term routine laboratory toxicity monitoring...
Energy-reduced Mediterranean diet with increased physical activity may significantly reduce risk of type 2 diabetes
1. In this secondary analysis of a randomized controlled trial, physical activity paired with an ad libitum energy-reduced Mediterranean diet...
Higher tetrahydrocannabinol exposure may be associated with unfavorable mental health outcomes
1. In this systematic review, higher levels of tetrahydrocannabinol exposure were associated with multiple unfavorable mental health outcomes, particularly for...
Clinically significant differences between different blood pressure measurement methods
1. In this systematic review and meta-analysis, estimated blood pressure was found to vary significantly between different methods, such as...
Intensive systolic blood pressure targets may be cost-effective across most measurement error possibilities
1. In this microsimulation model of patients with high cardiovascular risk, an intensive systolic blood pressure (SBP) target of <120...
