Carvedilol linked to lower cirrhosis complication risk
1. In this retrospective cohort study, carvedilol was associated with a lower risk of major liver decompensation compared with nadolol...
Telemedicine may reduce interhospital transfers without increasing mortality
1. In this systematic review and meta-analysis, telemedicine was associated with lower rates of interhospital transfer among both pediatric and...
Benzodiazepine use declined before the COVID-19 pandemic, then plateaued
1. In this retrospective cohort study, benzodiazepine use among US adults aged 65 years or older declined from 2015 to...
Sleep restriction promotes weight gain in high-risk adults
1. In this pooled analysis of randomized crossover trials, chronic mild sleep restriction was associated with modest increases in body...
Biweekly glucagon-like peptide-1 receptor agonist bofanglutide improves glycemic control
1. In this randomized controlled trial, biweekly injections of the novel glucagon-like peptide-1 receptor agonist (GLP-1RA) bofanglutide resulted in greater...
Lung cancer screening models show variable performance across populations
1. In this cohort study, 16 lung cancer risk prediction models demonstrated variation in screening efficiency and sensitivity across racial...
Concomitant COVID-19 and influenza vaccination not linked to increased adverse events
1. In this target trial emulation, same-day administration of COVID-19 and influenza vaccines was not associated with an increased risk...
Antibiotic prescribing remains high for uncomplicated diverticulitis
1. In this study, antibiotics were prescribed in nearly all visits for uncomplicated diverticulitis between 2015 and 2025, despite guideline...
Stockholm3 outperforms PSA for detecting significant prostate cancer
1. In this randomized screening trial, the multivariable Stockholm3 test provided greater clinical net benefit and substantially fewer false-negative results...
Telehealth yields modest improvements in diabetes outcomes
1. In this randomized trial, a comprehensive telehealth program produced modest but non-significant improvements in glycemic control compared with self-monitoring...
