Patient and provider characteristics associated with difficult clinical encounters
1. In this systematic review, 17% of primary care patients were perceived as difficult by physicians, particularly those with depression,...
Weekly islatravir plus lenacapavir maintains HIV virologic suppression
1. In this randomized controlled trial, once-weekly oral islatravir (ISL) plus lenacapavir (LEN) maintained high rates of HIV-1 virologic suppression...
Certain cannabis-based products may offer modest reductions in pain
1. In this updated systematic review, cannabis-based products with a comparable or high tetrahydrocannabinol (THC)-to-cannabidiol (CBD) ratio may provide a...
Bisphosphonates may reduce short-term pain in complex regional pain syndrome
1. In this systematic review and meta-analysis, bisphosphonates may reduce short-term (> 4 weeks to 3 months) pain in complex...
Reducing saturated fat decreases mortality in high-risk individuals
1. In this systematic review, reducing intake of saturated fatty acids (SFAs) showed possible benefit for mortality, non-fatal myocardial infarction...
Positive lung cancer screens frequently receive suboptimal follow-up
1. In this retrospective cohort study, most patients with a positive lung cancer screening result received guideline-concordant follow-up, though nearly...
Duration-based lung cancer screening may reduce racial disparities in eligibility
1. In this prospective cohort study, duration-based criteria reduced racial disparities in lung cancer screening eligibility, increasing access for minority...
GLP-1 receptor agonists show little effect on obesity-related cancer risk
1. In this systematic review and meta-analysis, use of glucagon-like peptide-1 receptor agonists (GLP-1RAs) was not associated with a significant...
Extended incubation period identified in novel mpox strain
1. This surveillance study suggests that the incubation period of mpox virus (MPXV) clade Ib may be slightly longer than...
Integrating methadone into primary care improves care quality
1. In this randomized controlled trial, integrating opioid agonist therapy (OAT) into primary care improved guideline-concordant health care while maintaining...
