Belimumab after rituximab reduces risk for severe flare in systemic lupus erythematosus
1. Belimumab combined with rituximab was shown to significantly reduce IgG anti-dsDNA antibody levels in patients with systemic lupus erythematosus....
Immune thrombocytopenia and thrombosis mortality predictors following SARS-CoV-2 vaccine
1. Low baseline platelet count and intracranial hemorrhage were shown to be prognostic mortality markers due to vaccine-induced immune thrombocytopenia...
Empaglifozin reduces death in heart failure patients with preserved ejection fraction
1. Empaglifozin treatment was shown to have reduced rates of cardiovascular death or hospitalization in patients with heart failure and...
Pembrolizumab after nephrectomy improves survival in renal-cell carcinoma patients
1. Patients receiving adjuvant pembrolizumab after nephrectomy for renal-cell carcinoma showed significantly improved disease-free survival compared to patients receiving placebo...
Complete revascularization guided by fractional flow reserve not superior to angiography
1. Revascularization guided by fractional flow reserve (FFR) was shown not to have significant benefit compared to angiography for patients...
Transglutaminase 2 inhibition attenuates mucosal injury in patients with celiac disease
1. ZED1227, a selective oral transglutaminase 2 inhibitor, was shown to reduce gluten-induced deterioration of intestinal mucosa in patients with...
Fetoscopic endoluminal tracheal occlusion improves infant survival for congenital diaphragmatic hernia
1. Fetoscopic endoluminal tracheal occlusion (FETO) was shown to improve survival to discharge in infants with severe left congenital diaphragmatic...
Tezepelumab reduced annual exacerbation rates in patients with severe asthma
1. Subcutaneous tezepelumab treatment reduced the rate of annual asthma exacerbations in patients with severe asthma compared to the placebo...
Prophylactic tranexamic acid prevents significant blood loss after cesarean delivery
1. Prophylactic tranexamic acid treatment was shown to lower the incidence of postpartum hemorrhage in women undergoing cesarean delivery. 2....
Sotatercept decreased vascular resistance in pulmonary arterial hypertension
1. Treatment with sotatercept decreased pulmonary vascular resistance in patients with pulmonary arterial hypertension. 2. Sotatercept caused adverse side effects...