![Novel biodegradable sirolimus-eluting stents non-inferior to durable everolimus-eluting stents [BIOSCIENCE trial]](https://www.2minutemedicine.com/wp-content/uploads/2014/09/Taxus_stent_FDA-e1607803635904-350x250.jpg)
Paclitaxel-coated devices do not reduce rates of major amputations in chronic limb-threatening ischemia
1. All-cause mortality and reduction in major amputations were similar between groups. 2. The rate of target vessel reintervention was...
Clopidogrel monotherapy is superior to aspirin for secondary prevention in coronary artery disease
1. Major adverse cardiovascular and cerebrovascular events were significantly reduced with clopidogrel compared to aspirin alone. 2. There was no...
Influenza vaccination improves survival and reduces readmissions in patients hospitalized for acute heart failure
1. All-cause mortality and hospital readmissions were significantly decreased with influenza vaccination compared to usual care. 2. Significantly fewer adverse...
Endoscopic sinus surgery improves quality of life compared with clarithromycin and placebo in chronic rhinosinusitis
1. Patients in the endoscopic sinus surgery group reported lower SNOT-22 scores at 6 months, suggesting improved quality-of-life metrics. 2....
Steroidal mineralocorticoid receptor antagonists show little mortality benefit in patients receiving dialysis
1. Cardiovascular mortality and heart failure-related hospitalization were slightly less in the steroidal MRA group, though there was no statistical...
Spironolactone does not reduce cardiovascular events in patients receiving maintenance dialysis
1. Cardiovascular mortality and heart failure-related hospitalization were similar in both groups. 2. There was no statistically significant difference between...
Efruxifermin improves fibrosis in patients with metabolic dysfunction-associated steatohepatitis
1. Efruxifermin 50 mg once-weekly significantly improved fibrosis at 96 weeks versus placebo. 2. MASH resolution without worsened fibrosis was...
Long term safety and efficacy of rabies monoclonal antibody in post-exposure prophylaxis
1. The rate of adverse events and seroresponse was similar between groups. 2. There were no incidents of rabies development...
Extended aromatase inhibitor therapy reduces breast cancer recurrence in postmenopausal women
1. Invasive breast cancer recurrence was significantly reduced with extended aromatase inhibitor therapy. 2. No significant reduction was noted for...
Talazoparib and enzalutamide improve survival in metastatic castration-resistant prostate cancer
1. Progression-free survival and overall survival were significantly greater in the combination therapy group compared to enzalutamide alone. 2. Anemia...
