Sitagliptin may reduce acute graft-versus-host disease following allogeneic stem-cell transplantation
1. While standard prophylaxis regimens against acute graft-versus-host disease (GVHD) are ineffective in a substantial portion of patients, less than 10% of patients who...
Schoolchildren aged 6-8 years experiencing increased prevalence of myopia following house confinement from COVID-19
1. Following a period of house confinement and online school due to COVID-19, the prevalence of myopia increased between 1.3 and 3.8 times in...
Oral azacytidine maintenance therapy improved survival outcomes in patients with acute myeloid leukemia
1. Oral azacytidine also known as CC-486 has been found to improve survival outcomes in patients with acute myeloid leukemia.
2. Frequently reported adverse events...
High fasting insulin levels in children associated with higher rates of psychosis and psychotic...
1. Persistently high fasting insulin levels were associated with psychosis and psychotic disorder later in life.
2. Major increases in body mass index during puberty...
Thirty minutes of moderate physical activity associated with significantly improved outcomes for patients with...
1. For older adults with overweight or obesity, and metabolic syndrome, replacing 30 minutes of inactive time with moderate to vigorous physical activity was...
Every-other-day dosing of oral rimegepant is effective for preventive treatment of migraines
1. Rimegepant significantly reduced the mean number of migraine days per month between the last 4 weeks of treatment and the observation period compared...
Lansoprazole not effective for the treatment of persistent throat symptoms
1. Lansoprazole was not found to be efficacious in the treatment of persistent throat symptoms.
Evidence Rating Level: 1 (Excellent)
Persistent throat symptoms are frequently encountered...
Global estimates show one third of the population may benefit from rehabilitation services
1. Approximately 1 in every 3 people worldwide (2.41 billion) could benefit from rehabilitation services with the Western Pacific region having the greatest need.
2....
Sleep disturbances in older adults linked to higher rates of multimorbidity
1. Moderate to severe sleep disturbances were associated with higher accumulation rates of chronic disease in older adults.
2. Moderate to severe sleep disturbances were...
