Metformin associated with retention of cognitive ability and reduced white matter loss in pediatric...
1. Metformin was found to be safe and tolerable in survivors of pediatric brain tumors.
2. Metformin was associated with retention of memory and processing...
Sodium glucose cotransporter-2 inhibitor use associated with increased risk of diabetic ketoacidosis
1. The use of sodium-glucose cotransporter-2 (SGLT-2i) increased study participants’ risk of diabetic ketoacidosis (DKA) hospital presentations when compared to dipeptidyl peptidase 4 inhibitors
2....
Modestly lower carbohydrate diet not associated with improved outcomes related to gestational diabetes
1. A modestly lower carbohydrate diet neither increased ketonemia nor improved glycemic control in pregnant women
Evidence Rating Level: 2 (Good)
Although meta-analyses have shown significant...
Kidney function in type 1 diabetes does not benefit from allopurinol therapy
1. Serum urate reduction with allopurinol was not shown to clinically benefit kidney function among patients with type 1 diabetes and early-to-moderate diabetic kidney...
Continuous glucose monitoring improves glycemic control in adolescents and young adults with Type 1...
1. Patients who used continuous glucose monitoring (CGM) showed significantly reduced glycated hemoglobin (HbA1C) levels compared to those who used standard blood glucose monitoring...
Gastric bypass surgery more effective than medical therapy alone for achieving microalbuminuria remission in...
1. Patients who underwent Roux-en-Y gastric (RYGB) surgery had higher rates of microalbuminuria remission when compared to those who received only medical treatment at...
Despite increasing cost of insulin, out-of-pocket expenses stable from 2006-2017
1. Insulin costs steadily increased from 2006-2017. However, the out-of-pocket costs to privately insured patients remained consistent, in-part due to decreased cost-sharing.
2. Privately insured...
Incidence of thyroid cancer in World Trade Center exposed firefighters
1. Fire Department World Trade Center-exposed workers demonstrate more asymptomatic thyroid cancers, attributable to occult lesion diagnoses, compared to non-WTC-exposed subjects of the Rochester...
Clinical report outlines health supervision recommendations for patients with achondroplasia
1. In this report, the American Academy of Pediatrics (AAP) provides updated guidelines on diagnosis, genetic counseling, medical evaluation, and anticipatory guidance for pediatricians...
Degarelix may be a treatment option for pedophilic disorder
1. Men with pedophilic disorder treated with gonadotropin-releasing hormone antagonist degarelix were at significantly lower risk of committing sexual abuse 2 weeks following initial...
