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The risk of thiazide-associated hyponatremia may be greatest in older women
1. Thiazide-associated hyponatremia is highly age and sex-dependent, with the greatest excess risk seen in older adults, especially women aged...
Endocrinology
Reports of high-impact endocrinology studies by medical professionals
Prednisone may have bone and cardiovascular benefits compared to hydrocortisone therapy in adrenal insufficiency
1. Prednisolone therapy is well tolerated, may have better bone and cardiovascular outcomes compared to hydrocortisone, and poses lower medication...
Lilly’s retatrutide achieves significant weight loss and A1C reduction in Phase 3 trial
1. Retatrutide met all major Phase 3 endpoints, delivering substantial reductions in both A1C and body weight in patients with...
2 Minute Medicine: Pharma Roundup – Pfizer’s Talzenna delays prostate cancer progression, apixaban lowers VTE bleeding risk, Lilly’s retatrutide hits Phase III metabolic targets, and FDA warns Novo Nordisk over safety reporting violations [March 2026]
Pfizer’s Talzenna combo significantly delays progression in frontline prostate cancer Topline results from the Phase 3 TALAPRO-3 study indicate that...
Dipeptidyl peptidase-4 inhibitors may be associated with an increased incidence of malignancy
1. Sitagliptin demonstrated the most prominent malignancy-related safety signal among the dipeptidyl peptidase-4 inhibitors studied. Evidence Rating Level: 2 (Good) ...
Finerenone improves albuminuria in adults with type 1 diabetes and chronic kidney disease
1. In this phase 3 trial involving patients with type 1 diabetes and chronic kidney disease, finerenone was associated with...
Glucagon-like peptide-1 receptor agonists are associated with reduced risk of developing substance use disorders
1. Use of glucagon-like peptide-1 (GLP-1) receptor agonists was associated with reduced risk of developing substance use disorders among US...
Prenatal depression and gestational diabetes are associated with increased risk of childhood obesity
1. Prenatal depression and gestational diabetes were independently associated with a higher risk of childhood obesity within the first 10...
Glucagon-like peptide-1 receptor agonists may reduce endometrial cancer risk in endometrial hyperplasia
1. Glucagon-like peptide-1 receptor agonists (GLP-1RA) in combination with progestins are significantly more effective at reducing endometrial cancer (EC) risk...
Sleeve gastrectomy may produce greater and more durable weight loss than semaglutide in patients with obesity
1. Sleeve gastrectomy produces substantially greater and more durable weight loss than semaglutide over 12 months in patients with obesity....
