Radical cure with primaquine reduces risk of Plasmodium vivax parasitaemia in patients with Plasmodium falciparum infection
1. Patients in the primaquine group reported a significant reduction in parasitemia risk at day 63 compared to those in...
Hematology
Statin use may reduce risk of venous thromboembolism in women taking hormone therapy
1. In this case-control study, the use of statins in menopausal women concurrently with hormone therapy (HT) significantly reduced the...
Thalidomide reduces recurrent bleeding from small-intestinal angiodysplasia
1. In this randomized controlled trial, thalidomide resulted in a dose-dependent reduction in bleeding among patients with recurrent bleeding from...
Edoxaban does not improve outcomes in patients with atrial high-rate episodes
1. In this randomized controlled trial, edoxaban did not significantly reduce the incidence of a composite of cardiovascular death, stroke,...
Physical activity following a deep vein thrombosis reduces the severity of post-thrombotic syndrome
1. This systematic review found that early mobilization in the acute phase following a deep vein thrombosis (DVT) was associated...
![CRISPR-mediated gene activation rescues obesity caused by haploinsufficiency [PreClinical]](https://www.2minutemedicine.com/wp-content/uploads/2019/03/CRISPR-350x250.jpg)
CRISPR-Cas9 promoting fetal hemoglobin production improves severe sickle cell disease
1. In this randomized controlled trial, infusion of OTQ923 disrupted inhibitory HBG1 and HBG2 promoter regions of the gamma-globin gene....
Concizumab reduces bleeding episodes in hemophilia patients with inhibitors
1. In this phase three open-label randomized trial, concizumab prophylaxis reduced the annualized bleeding rate in patients with hemophilia with...
Lisocabtagene maraleucel may induce remission in relapsed chronic lymphocytic leukemia (CLL)
1. Complete response or remission was reported in 18% of patients who received a single liso-cel infusion. 2. Nearly 10%...
Survivors of childhood cancer are less active than their peers
1. In a cross-sectional study, adolescent survivors of childhood cancers were more sedentary than age-matched controls. 2. Age, gender, BMI,...
Prehospital administration of tranexamic acid for major traumas does not improve outcomes
1. In this randomized controlled trial, for adults with major trauma or trauma-induced coagulopathy, prehospital administration of tranexamic acid did...
