1. New-onset atrial fibrillation following hospitalization for community acquired pneumonia was associated with higher subsequent thromboembolic risk. Evidence Rating Level:...
1. Compared to placebo and azacytidine, the combination of ivosidenib and azacitidine demonstrated significant clinical benefit for IDH1-mutated acute myeloid...
1. Compared to placebo, mitapivat was found to be effective in treating hemolytic anemia and increasing hemoglobin levels. 2. Mitapivat...
1. Rilzabrutinib was active and 400mg twice daily was identified as the dose for further testing with low-level toxic effects....
1. Asundexian 50 mg resulted in a lower rate of bleeding compared to apixaban 5 mg twice daily. 2. The...
1. This trial demonstrated noninferiority of daprodustat to darbepoetin alfa in the treatment of anemia in patients with chronic kidney...
1. In a large longitudinal, population-based cohort study, SARS-CoV-2 infection during pregnancy was associated with severe maternal morbidity, preterm birth,...
1. Patients with hereditary angioedema receiving donidalorsen showed reduced rates of angioedema attacks compared to patients receiving placebo treatment. 2....
1. The adeno-associated virus 5 (AAV5)-based gene therapy, valoctocogene roxaparvovec (AAV5-hFVIII-SQ), resulted in sustained factor VIII production, reduced bleeding rates,...
1. Garadacimab significantly reduced the number of monthly attacks in patients with hereditary angioedema compared to placebo. 2. No serious...
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