Low-dose yellow fever vaccine non-inferior to standard dose
1. This randomized controlled trial conducted in Kenya and Uganda assessed whether fractional doses of the 17D-204 yellow fever vaccine...
Infectious Disease
Reports of high-impact infectious disease studies by medical professionals
Emerging highly pathogenic avian influenza A(H5N1) infections in humans
1. In this case series, of the reported 46 case-patients, 45 cases were due to exposures to infected poultry or...
Mpox cases in Africa continued to increase following WHO emergency declarations
1. The number of mpox cases in Africa increased leading up to the first mpox declaration of a Public Health...
Avian Influenza A(H5N1) caused mild illness in the exposed U.S. population
1. In this case series, agricultural workers who contracted A(H5N1) experienced mild illnesses of short duration, with no reported fatalities....
Levofloxacin shows limited efficacy in preventing multidrug-resistant tuberculosis
1. In this randomized controlled trial, daily levofloxacin treatment in patients with multidrug-resistant (MDR) or rifampicin-resistant Mycobacterium tuberculosis did not...
Levofloxacin does not prevent infection in children exposed to MDR tuberculosis
1. In this randomized controlled trial, among children and adolescents with household exposure to an adult with multidrug-resistant tuberculosis, it...
rVSV-ZEBOV-GP ring vaccination reduces the incidence of Ebola virus disease
1. In the outbreak of Ebola virus disease (EVD) in the Democratic Republic of Congo (DRC) between 2018 and 2020,...
Bedaquiline monotherapy may be effective at improving multibacillary leprosy.
1. In this proof-of-concept study, bedaquiline therapy cleared Mycobacterium leprae by four weeks of treatment in patients with multibacillary leprosy....
SEP-1 sepsis management bundle not associated with improved mortality
1. In this systematic review, there was minimal evidence of improved sepsis mortality with implementation of the Severe Sepsis and...
Increased blood–urea–nitrogen-to-albumin ratio associated with increased mortality in coronavirus disease
Association between blood–urea–nitrogen-to-albumin ratio and in-hospital mortality in patients diagnosed with coronavirus disease 2019: a retrospective cohort study 1. Increased...
