Nephrology

Reports of high-impact nephrology studies by medical professionals

Gastric bypass surgery more effective than medical therapy alone for achieving microalbuminuria remission in...

1. Patients who underwent Roux-en-Y gastric (RYGB) surgery had higher rates of microalbuminuria remission when compared to those who received only medical treatment at...

Long-term use of rituximab associated with lower rates of AAV relapse

1. In this randomized controlled trial involving patients with antineutrophil cytoplasmic antibody-associated vasculitis in complete remission, administration of rituximab for an additional 18 months...

Antihypertensive medications and risk of COVID-19

1. Amongst the five examined classes of antihypertensive medications (ACE Inhibitors, ARBs, beta blockers, calcium-channel blockers, and thiazide diuretics), none were associated with a...

Error in GFR calculation with exclusion of patient race

1. The exclusion of patient race from glomerular filtration rate (GFR) estimation resulted in systematic error that significantly underestimated GFR in African American individuals...

Febuxostat not effective at delaying progression of carotid atherosclerosis in asymptomatic hyperuricemia

1. While there was no placebo control group, treatment with febuxostat for 24 months did not slow carotid atherosclerosis progression in Japanese individuals with...

Comparison of Cardiovascular and Safety Outcomes of Chlorthalidone vs Hydrochlorothiazide to Treat Hypertension

1. While chlorthalidone is the recommended thiazide diuretic treatment for hypertension, it has no added benefits compared to hydrochlorothiazide and has significantly worse safety...

Difelikefalin associated with reductions in itch intensity and improvements in itch-related quality of life

1. In this double-blind phase 3 trial involving patients undergoing hemodialysis who had moderate-to-severe pruritus, a clinically significant decrease in itching intensity was noted...

Low risk of nephrogenic systemic fibrosis with group II gadolinium contrast agents in chronic...

1. In a systematic review and meta-analysis of the use of group II (low risk) gadolinium-based contrast agents (GBCA) for MRI in patients with...

Polypill effective for blood pressure and cholesterol control in vulnerable population

1. In this randomized, controlled trial, patients without cardiovascular disease randomized to receive a polypill containing atorvastatin, amlodipine, losartan, and hydrochlorothiazide experienced greater reductions...

Downward trend in mortality rate for antineutrophil cytoplasmic autoantibody-associated vasculitis

1. In this study of decedents from 1999 to 2017, mortality due to antineutrophil cytoplasmic autoantibody-associated vasculitis (AAV) -related illness was found to have...

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