Semaglutide and tirzepatide may be cost-effective for knee osteoarthritis in patients with obesity
1. In this microsimulation model, the two glucagon-like peptide-1 receptor agonists were shown to be cost-effective when added to usual...
Orthopedic Surgery
Use of a valgus brace may reduce knee pain in knee osteoarthritis
1. After six months, valgus brace users with knee osteoarthritis reported a statistically significant and clinically meaningful reduction in knee...
Medical cannabis has a high discontinuation rate for treatment of musculoskeletal pain
1. Medical cannabis has a high discontinuation rate among patients with chronic musculoskeletal pain, particularly in the first few months,...
Very-low-calorie diets versus exercise alone for the treatement of hip osteoarthritis
1. In this randomized controlled trial, a very-low-calorie diet plus exercise was not superior to exercise alone in reducing hip...
Medial opening wedge high tibial osteotomy associated with improved outcomes in knee osteoarthritis with varus alignment
1. In this randomized trial, patients with medial compartment knee osteoarthritis who received medial opening wedge high tibial osteotomy had...
Casting only may be non-inferior to surgery for management of medial epicondyle fractures
1. Casting only was non-inferior compared to surgical treatment in the management of children with medial epicondyle fractures. Evidence Rating...
Physical therapy vs. glucocorticoid injection in patients with meniscal tears and knee osteoarthritis
1. Patients with meniscus tears and knee osteoarthritis (KOA) who were randomized to physical therapy experienced improved pain and quality...
Pembrolizumab with radiotherapy and surgery improves survival in high-risk soft tissue sarcoma
1. Pembrolizumab plus radiotherapy and surgery significantly improved disease-free survival. 2. Grade 3 or higher adverse events were more common...
Hip replacement superior to resistance training in severe hip osteoarthritis
1. In this randomized controlled trial, total hip replacement (THR) was superior to resistance training in improving hip pain and...
Double dose extracorporeal shockwave may be more effective for plantar flexor spasticity of ankle in stroke patients
1. Double-dose ESWT to the gastrocnemius and soleus showed greater improvements in post-stroke ankle plantar flexor spasticity Evidence Rating Level:...
