Pembrolizumab with radiotherapy and surgery improves survival in high-risk soft tissue sarcoma
1. Pembrolizumab plus radiotherapy and surgery significantly improved disease-free survival. 2. Grade 3 or higher adverse events were more common...
Orthopedic Surgery
Hip replacement superior to resistance training in severe hip osteoarthritis
1. In this randomized controlled trial, total hip replacement (THR) was superior to resistance training in improving hip pain and...
Double dose extracorporeal shockwave may be more effective for plantar flexor spasticity of ankle in stroke patients
1. Double-dose ESWT to the gastrocnemius and soleus showed greater improvements in post-stroke ankle plantar flexor spasticity Evidence Rating Level:...
Individualized walking and education program reduces the recurrence of low back pain
1. Walking significantly reduced low-back pain recurrence compared to the control group. 2. Patients in the walking group saved approximately...
Low-volume local anesthetic with intravenous dexamethasone may provide superior efficacy for shoulder arthroscopy
1. Low-volume local anesthetic with intravenous dexamethasone reduced the incidence of diaphragmatic paresis and provided equivalent analgesic duration compared to...
Early weight-bearing after ankle surgery may be as effective and more cost-efficient than delayed weight-bearing
1. Patients in the early weight-bearing group showed better recovery than those in the delayed weight-bearing group at 4 months...
Vimseltinib may be promising in treating symptomatic tenosynovial giant cell tumour
1. Tumor response rate at 25 weeks was significantly greater in vimseltinib than placebo. 2. Most adverse events were mild-to-moderate...
Comparison of hip fracture risk assessment tools for elderly patients
1. Femoral neck bone mineral density (FNBMD) alone discriminated 5-year hip fracture risk at least as well as FRAX and...
Total knee arthroplasty with MAKO robot assistance may improve surgical outcomes
1. Total knee arthroplasty (TKA) using a MAKO robot improves short-term efficacy and can assist in planning while maintaining high...
Corticosteroid injections not found to be associated with fracture risk in elderly cohort
1. In a cohort of older adults, the use of corticosteroid injections (CSIs) was not associated with increased fracture risk,...