Increased cardiorespiratory fitness may lower high blood pressure in children
1. Higher cardiorespiratory fitness was associated with a decreased probability of high blood pressure, lowered insulin resistance and improved liver...
Pediatrics
Reports of high-impact pediatrics studies by medical professionals
Sweat chloride levels predict future cystic fibrosis diagnosis in those with inconclusive diagnosis at birth
1. In a prospective multi-center study, 21% of children with cystic fibrosis screen positive, inconclusive diagnosis (CFSPID) at birth were...
Maternal genetic risk of hypertension associated with reduced placental weight
1. Maternal genetic risk of hypertension is associated with reduced placental weight, inhibiting fetal growth and contributing to future cardio-metabolic...
Amoxicillin shows no benefit in children with uncomplicated lower respiratory tract infections
1. Between a 7-day course of amoxicillin or placebo, there was no significant different in symptom duration and no clinically...
Maralixibat appears safe and efficacious for patients with Alagille syndrome and cholestatic pruritus
1. Switching to placebo after week 18 resulted in greater elevations in serum bile acid levels and pruritus compared to...
Low-to-Moderate caffeine intake during pregnancy is not associated with increased risk of maternal cardiometabolic complications
1. A cohort study of 2583 pregnant women found that low or moderate caffeine intake (<200mg/day) did not significantly increase...
Intranasal surfactant does not improve outcomes for children with acute otitis media
1. In a randomized controlled trial (RCT) of over 100 children aged 6-24 months with acute otitis media, adding intranasal...
Diabetic ketoacidosis not associated with poor long-term metabolic control in children
1. In children with type 1 diabetes, diabetic ketoacidosis is not associated with poor long-term metabolic control. Evidence Rating Level:...
Intranasal oxytocin showed no benefits for pediatric autism spectrum disorder
1. Intranasal oxytocin was shown not to impact social interaction scores in children and adolescents with autism spectrum disorder (ASD)....
Interpersonal discrimination associated with poorer mental health, wellbeing, and substance use in young adults
1. This large study of a nationally representative sample of young adults found that over 90% had experienced some form...
Popular Reports
Peripherally inserted central catheters are associated with twice as many complications than midline catheters when used short-term
Capecitabine + oxaliplatin chemoradiotherapy does not increase survival, but increases toxicity, compared to capecitabine alone in the postoperative treatment of rectal cancer
The Child-Pugh score: Prognosis in chronic liver disease and cirrhosis [Classics Series]
Ultrasound features associated with shoulder complaints
Automated pupillometry may be helpful in opioid agonist therapy dosing for opioid use disorder
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