Genomic sequencing identifies variants linked to congenital diarrhea and enteropathies
1. In this cross-sectional study, nearly half of the infants with congenital diarrhea and enteropathies (CODEs) had identifiable causal variants,...
Pediatrics
Reports of high-impact pediatrics studies by medical professionals
Higher nicotine consumption observed among youth with attention-deficit hyperactivity disorder
1. This cohort of United States youths with asymptomatic attention-deficit hyperactivity disorder (ADHD), did not have statistically significant differences in...
Infigratinib shows promising efficacy and tolerability in pediatric achondroplasia
1. In this phase two dose-finding study in children with achondroplasia, daily oral Infigratinib did not lead to any grade...
Depemokimab therapy reduces exacerbations in patients with severe eosinophilic asthma
1. In this randomized, placebo-controlled replicate trial, depemokimab decreased the annual rate of exacerbations among patients with severe eosinophilic asthma....
Levofloxacin does not prevent infection in children exposed to MDR tuberculosis
1. In this randomized controlled trial, among children and adolescents with household exposure to an adult with multidrug-resistant tuberculosis, it...
Characterization of meconium-related obstruction and outcomes in term and preterm infants
Meconium-Related Obstruction and Clinical Outcomes in Term and Preterm Infants 1. Nearly 95% of cases of meconium-related obstruction (MRO) occur...
Certain childhood body sizes and compositions associated with increased risk of incident hypertension
1. In this cohort of adults in the United Kingdom (UK), those with a thinner or plumper body size in...
Ultraprocessed food consumption comprises high proportion of energy intake in obese Canadian children
1. In a cohort of Canadian children, higher ultraprocessed food (UPF) consumption comprised almost half of their energy intake. Evidence...
Prenatal systemic glucocorticoid exposure may be associated with increased risk of future mental disorder
1. In this cohort study of offspring born to mothers at risk for preterm delivery or diagnosed with an autoimmune...
Adalimumab may be associated with improved outcomes in the management of pediatric Crohn’s disease
1. Maintenance therapy with adalimumab (ADA) was associated with more frequent objective improvement based on Magnetic Resonance Enterography (MRE) findings...