Integrating methadone into primary care improves care quality
1. In this randomized controlled trial, integrating opioid agonist therapy (OAT) into primary care improved guideline-concordant health care while maintaining...
Pharma
Biomarker-Guided Cardioprotection for Patients Treated With Anthracyclines
1. An N-terminal pro–B-type natriuretic peptide (NT-proBNP)-guided approach to neurohormonal therapy for cardioprotection in patients receiving anthracyclines for breast cancer...
Efficacy of standard care versus acoustic therapy on acute tinnitus in idiopathic sudden sensorineural hearing loss: a randomized controlled trial
1. For adults with idiopathic sudden sensorineural hearing loss and acute tinnitus, short-course inpatient personalized acoustic therapy may increase long-term...
Opioid overdose associated with concomitant use of hydrocodone and selective serotonin reuptake inhibitors
1. Sertraline appears to be the safest selective serotonin reuptake inhibitor (SSRI) option for patients taking hydrocodone because it is...
Comparison of two different bicarbonate replacement fluids during continuous veno-venous hemofilitration with regional citrate anticoagulation: a prospective, randomized, controlled trial
1. Low bicarbonate replacement fluid (LBF) leads to more stable pH and HCO3− compared to high bicarbonate replacement fluid (LBF)...
Identification of NSTE-ACS patients with totally occluded infarct-related artery: the role of the SAVE risk score in improved risk stratification
1. The novel SAVE risk score is effective at identifying non-ST-segment elevation acute coronary syndrome (NSTE-ACS) patients with totally occluded...
Selective serotonin reuptake inhibitors do not affect cognitive function through breastmilk
1. In this prospective cohort study, postpartum selective serotonin reuptake inhibitors (SSRIs) use during breastfeeding was not associated with reduced...
Vernakalant versus procainamide for rapid cardioversion of patients with acute atrial fibrillation (RAFF4): randomised clinical trial
1. Vernakalant was superior to procainamide for rapid cardioversion of patients with acute atrial fibrillation, with a higher conversion rate...
Diphenhydramine, Sodium Bicarbonate, or Combination for Acute Peripheral Vertigo: A Randomized Clinical Trial
1. In this randomized clinical trial, combination therapy with diphenhydramine and sodium bicarbonate was associated with decreased vertigo compared to...
Diphenhydramine, Sodium Bicarbonate, or Combination for Acute Peripheral Vertigo
1. Intravenous diphenhydramine and sodium bicarbonate together are significantly more effective than diphenhydramine alone at reducing the severity of acute...
