Pulmonology

Reports of high-impact pulmonology studies by medical professionals

Probiotics not effective at reducing incidence of ventilator-associated pneumonia in critically ill patients

1. The administration of the probiotic Lactobacillus rhamnosus GG resulted in no significant difference compared to placebo in the development of ventilator-associated pneumonia in...

Risk prediction of COVID-19 related death and hospital admission in adults after COVID-19 vaccination

1. Out of 5,150,310 individuals in England that received two COVID-19 vaccine doses, 81 patients passed away  from COVID-19 and 71 were admitted to hospital for...

Gemcitabine with ramucirumab improved overall survival for malignant pleural mesothelioma

1. Compared to the gemcitabine with placebo group, the gemcitabine with ramucirumab group had longer overall survival as a potential second-line treatment for malignant...

Heterologous ChAdOx1 prime-boosted vaccination schedules are non-inferior to homologous vaccination

1. Heterologous AstraZeneca followed by Pfizer vaccination was noninferior to homologous, two-dose AstraZeneca vaccination with a geometric mean ratio of 9.2. 2. Heterologous Pfizer followed...

Inhaled budesonide shortens time to recovery for high-risk COVID-19 patients in the community

1. Time to recovery was lower in patients assigned to budesonide compared to usual care, meeting the superiority criteria. 2. Rate of hospitalizations or death...

Association of age and pediatric household transmission of SARS-CoV-2 infection

1. Children aged 0 to 3 years old were more likely than children aged 14 to 17 to transmit SARS-CoV-2 to other household members. Evidence...

Milrinone and dobutamine show no difference for cardiogenic shock treatment

1. Milrinone was shown not to be significantly different than dobutamine for the treatment of cardiogenic shock. 2. In-hospital deaths of patients treated with either...

Metformin does not improve the progression-free survival of stage IIIA or IIIB locally advanced...

1. Metformin, in addition to standard chemoradiation therapy, did not improve the progression-free survival, overall survival, local-regional recurrence, or distant metastasis occurrence compared to...

Canakinumab not associated with increased survival without invasive mechanical ventilation among patients hospitalized with...

1. Among patients hospitalized with severe COVID-19 and hyperinflammation, treatment using the anti-interleukin-1β antibody canakinumab, compared with placebo, did not significantly increase the likelihood...

Study highlights trends and outcomes of bronchodilator use in infants with bronchiolitis

1. In a large retrospective study, the rate of bronchodilator use during emergency visits for infants with bronchiolitis decreased from 51.5% to 22.8% between...

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