Biomarkers distinguish pediatric musculoskeletal infections from similar conditions
1. In a prospective cohort study, white blood cell (WBC) count, absolute neutrophil count (ANC), C-reactive protein (CRP), erythrocyte sedimentation rate...
Rheumatology
Peresolimab reduces disease severity in adults with rheumatoid arthritis
1. In this randomized controlled trial, there was a significant reduction in the Disease Activity Score of rheumatoid arthritis patients...
Sparsentan superior to irbesartan for reduction of proteinuria in patients with IgA nephropathy
1. Patients in sparsentan group reported a 50% reduction in proteinuria compared to 15% in the irbesartan group at week...
Ritlecitinib superior to placebo in the treatment of alopecia areata among teens and adults
1. Patients in the ritlecitinib group showed significant improvements in alopecia symptoms, with Severity of Alopecia Tool (SALT) scores ≤...
Price changes in colchicine have changed practice management for gout
1. The price increase of Colchicine in the United States led to greater use of alternative medications for gout treatment,...
Musculoskeletal disease likely a risk factor for development of dementias
1. Participants reporting a greater number of chronic pain sites had a higher proportion of developing incident all-cause dementia, AD,...
C-reactive protein may have superior prognostic value compared to low-density lipoprotein cholesterol for patients on statin therapy
1. High-sensitivity C-reactive protein increased the risk of all-cause mortality by two- to three-fold among all three randomized trials. 2....
Etrasimod improves clinical remission rates in patients with moderate-severe ulcerative colitis
1. In both ELEVATE UC 12 and ELEVATE UC 52, significantly greater patients in the etrasimod group achieved clinical remission...
Minimalist footwear reduces patellofemoral joint loads during running
1. In this systematic review and meta-analysis, it was found that minimalist footwear reduced the load experienced by the patellofemoral...
Secukinumab reduces symptoms of moderate-to-severe hidradenitis suppurativa
1. Patients receiving secukinumab every 2-weeks showed superior clinical response rates compared to those receiving placebo. 2. Secukinumab was well-tolerated,...
