Olaparib improves the quality of life for metastatic castration-resistant prostate cancer patients
1. Olaparib led to a bigger decrease in pain interference and symptomatic skeletal-related events than hormonal drugs. 2. Olaparib demonstrated...
Urology
Reports of high-impact urology studies by medical professionals
Abiraterone acetate improves survival in high-risk non-metastatic prostate cancer
1. Abiraterone acetate plus standard treatment significantly increased length of metastasis-free survival in men with non-metastatic prostate cancer compared to...
Androgen deprivation therapy is not associated with overall mortality in prostate cancer patients with COVID-19
1. In this retrospective cohort study, there was no significant difference in all-cause mortality between patients with prostate cancer and...
Prostate-Specific Membrane Antigen Positron Emission Tomography can be used to detect pelvic lymph nodes in prostate cancer
1. For the detection of pelvic nodal metastases in men with intermediate-to high-risk prostate cancer, using the 68Ga-PSMA-11 PET scan,...
Magnetic resonance imaging-targeted biopsy noninferior to standard biopsy for prostate cancer screening
1. Magnetic resonance imaging with targeted and standard biopsy was non-inferior for the detection of clinically significant cancers compared to...
7-day antibiotic therapy is noninferior to 14-day therapy in afebrile men with urinary tract infection
1. A double-blinded, randomized controlled trial found that there were no significant differences between afebrile men treated for 7 days...
Ipatasertib plus abiraterone significantly improves survival in patients with PTEN-negative prostate cancer compared to abiraterone alone
1. Ipatasertib-abiraterone treatment significantly improved progression-free survival compared to placebo-abiraterone in patients with PTEN-loss metastatic castration-resistant prostate cancer. 2. Grade...
Guideline-concordant multimodal therapy associated with improved mortality outcomes in patients with high-risk prostate cancer
1. Among patients with high-risk prostate cancer receiving guideline-concordant multimodal therapy, prostate cancer-specific mortality outcomes were equivalent among radical prostatectomy,...
Routine urinary tract cancer testing among all patients with microhematuria has low diagnostic yield
1. Evaluation with cystoscopy and CT urography for patients presenting with microhematuria (MH) had a low diagnostic yield for urinary...
Enfortumab vedotin prolongs survival in previously treated advanced urothelial carcinoma
1. Enfortumab vedotin showed improved overall survival when compared to chemotherapy in patients with previously treated advanced urothelial carcinoma. 2....
