Crinecerfont facilitates glucocorticoid dose reduction in pediatric congenital adrenal hyperplasia
1. In this randomized controlled trial of pediatric patients with congenital adrenal hyperplasia (CAH), it was found that treatment with...
Pediatrics
Reports of high-impact pediatrics studies by medical professionals
Risk factors for recurrent firearm injury among children
1. In this retrospective observational cohort study of children in St. Louis, those with the highest risk of firearm injury...
Plasma biomarkers may have a role in adolescent traumatic brain injuries
1. GFAP, UCH-L1, NfL, and t-tau are all promising plasma biomarkers that show sex specific changes in adolescents post sport-related...
Twice-yearly azithromycin distribution reduces childhood mortality in rural Niger
1. In this randomized cluster trial, twice-yearly azithromycin distribution reduced all-cause childhood mortality among children aged one to 59 months...
Oseltamivir and peramivir may reduce length-of-hospital-stay in patients with severe influenza
1. Time in hospital was modestly reduced in both intervention groups compared to the control. 2. There was little to...
Phase I trial of novel CAR-T cell therapy for pediatric midline gliomas
1. Approximately 88% of patients with GD2-positive diffuse midline glioma or other progressive CNS tumours receiving C7R-GD2.CARTs had a partial...
Ultraprocessed food consumption associated with cardiometabolic risk factors in children
1. Preschool-aged children in the top tertile of unprocessed food (UPF) consumption had significantly higher body-mass index (BMI), waist circumference,...
Overground robot-assisted gait training may be effective in children with cerebral palsy
1. Overground Robot-assisted gait training (RAGT), using a new torque-assisted wearable exoskeletal robot significantly improved gross motor function and gait...
Efanesoctocog alfa in children with hemophilia A reduces bleeding
1. In this randomized controlled trial, a prophylactic weekly dose of efanesoctocog alfa (ALTUVIIIO) resulted in sustained factor VIII activity...
COVID-19 vaccination and infection not associated with increased risk of congenital anomalies
1. In a cohort of infants born to mothers during the COVID-19 pandemic, neither vaccination nor infection with COVID-19 led...
