![ABCD2 Score: Predicting Early Stroke Risk After Transient Ischemic Attack (TIA) [Classics Series]](https://www.2minutemedicine.com/wp-content/uploads/2013/05/web-cover-classics-with-logo-medicine-BW-small-jpg-350x250.jpg){kind=logo}
STOP-IT Trial: Fixed-Duration Antibiotic Therapy for Intraabdominal Infections [Classics Series]
1. The STOP-IT trial found that 4 days of fixed antibiotic therapy after surgical or percutaneous source control is as...
Infectious Disease Classics
Landmark studies in infectious disease, organized using 2 Minute Medicine’s The Classics table of contents.
Zidovudine reduces maternal-infant HIV transmission [Classics Series]
1. Among pregnant women with HIV, antepartum, intrapartum and neonatal zidovudine therapy reduced maternal-fetal transmission of HIV by two-thirds. Original...
HPV triage is optimal management for ASCUS [Classics Series]
1. A single human papillomavirus (HPV) test identified 92.4% of women diagnosed with CIN-III. 2. A strategy of HPV triage...
Albumin in cirrhotic patients with spontaneous bacterial peritonitis [Classics Series]
1. In cirrhotic patients with spontaneous bacterial peritonitis, albumin infusion on days 1 and 3 of treatment in addition to...
Fecal transplantation in recurrent C. difficile infection [Classics Series]
1. Treating recurrent C. difficile infection with infusion of donor feces resulted in significantly higher cure rates than treating with...
Antibiotic GBS prophylaxis linked to decreased early-onset neonatal infection [Pediatrics Classics Series]
Image: PD 1. During the 1990-1998 study period, which included the 1996 initiation of national Group B Streptococcus guidelines, a...
Fidaxomicin vs. vancomycin in C. difficile infection [Classics Series]
1. Fidaxomicin is non-inferior to vancomycin in achieving clinical cure of C. difficile infection 2. Fidaxomicin therapy significantly reduces the...
Quadrivalent HPV vaccine in young women [Classics Series]
Image: PD 1. Prophylactic use of a quadrivalent vaccine against HPV strains 6, 11, 16, and 18 significantly reduced the...
Initial guidelines for prolonged fever in children [Pediatrics Classics Series]
Image: PD 1. Among 100 children presenting to one children’s hospital for prolonged febrile illnesses, the majority of cases were...
Prophylactic penicillin and reduced septicemia in sickle cell patients [Pediatrics Classics Series]
Image: PD 1. This randomized, placebo-controlled, double-blinded trial demonstrated an 84% reduction in the incidence of pneumococcal septicemia among patients...
