Early retroviral therapy reduces HIV-1 transmission [Classics Series]
Image: PD 1. HIV-1 transmission rates were significantly lower in the early-therapy group compared to the delayed-therapy group 2. Patients...
Infectious Disease Classics
Landmark studies in infectious disease, organized using 2 Minute Medicine’s The Classics table of contents.
Tenofovir-emtricitabine more effective and safer than zidovudine-lamivudine in HIV treatment [Classics Series]
Image: PD 1. A significantly higher percentage of patients taking tenofovir, emtricitabine, and efavirenz had HIV viral load <50 copies/mL...
RSV positivity associated with reduced serious bacterial infection risk [Classics Series]
Image: PD 1. RSV-positive infants were significantly less likely to have an SBI than those who tested negative (7% vs....
Clinical prediction rule stratifies pediatric bacterial meningitis risk [Classics Series]
Image: PD 1. A Bacterial Meningitis Score of 0 accurately identified all children with aseptic meningitis in the study’s validation group. 2....
Experimental gene therapy results in full clinical reversal of X-linked SCID [Classics Series]
Image: PD 1. Two patients with X-linked severe combined immunodeficiency (SCID) were treated with a retroviral-vector containing γc receptor for...
The CURB-65 score: Risk stratifying patients with community-acquired pneumonia [Classics Series]
1. Patients with community-acquired pneumonia (CAP) can be stratified into mortality risk groups using a five-point score. 2. One point...
Vancomycin superior to metronidazole for severe C. difficile diarrhea [Classics Series]
Image: PD 1. Metronidazole and vancomycin had similar efficacy in treating mild cases of Clostridium difficile-associated diarrhea (CDAD). 2. Vancomycin...
Early initiation of antiretroviral therapy significantly improves HIV survival [Classics Series]
Image: CC/L. academia 1. The relative risk of death was significantly higher in patients who deferred antiretroviral therapy compared to those...
Adjuvant dexamethasone improves outcomes in adult bacterial meningitis [Classics Series]
Image: CC/L. academia 1. Treatment with dexamethasone reduces morbidity and mortality in adults with bacterial meningitis 2. There is no significant...
