Zidovudine reduces maternal-infant HIV transmission [Classics Series]
1. Among pregnant women with HIV, antepartum, intrapartum and neonatal zidovudine therapy reduced maternal-fetal transmission of HIV by two-thirds. Original...
Obstetrics and Gynecology Classics
Doppler velocimetry of fetal middle cerebral artery predicts anemia [Classics Series]
1. Among fetuses at risk for maternal red cell alloimmunization, peak systolic velocity in the middle cerebral artery is a...
The ORACLE trial: Antibiotics for preterm, prelabor rupture of membranes [Classics Series]
1. Among infants born to women with preterm, premature rupture of membranes, those whose mothers were randomized to treatment with...
Head cooling improves outcomes in neonatal encephalopathy [Classics Series]
1. Among term infants with neonatal encephalopathy associated with mild EEG changes, those randomized to head cooling had a reduced...
The HAPO trial: hyperglycemia and adverse pregnancy outcomes [Classics Series]
1. Impaired glucose tolerance on the 2-hour glucose tolerance test was associated with increased odds of primary cesarean delivery, large...
Gestational diabetes treatment improves maternal outcomes [Classics Series]
1. Women randomized to treatment of mild gestational diabetes were less likely to experience shoulder dystocia, cesarean delivery, gestational hypertensive...
Letrozole superior to clomid for ovulation induction in PCOS [Classics Series]
1. Women with polycystic ovary syndrome (PCOS) randomized to receive letrozole had more live births than women randomized to clomiphene...
The Women’s Health Initiative: Risks outweigh benefits of combination hormone replacement therapy [Classics Series]
1. Combination estrogen and progestin hormone replacement therapy (HRT) is associated with a 29% increased risk of cardiovascular disease, 110%...
Twin vaginal delivery as safe as cesarean [Classics Series]
1. Among women with cephalic-presenting diamniotic twins at term, those randomized to planned cesarean delivery were not more likely to...
Most ovarian cysts resolve, sonographic surveillance recommended [Classics Series]
1. The majority (>60%) of ovarian abnormalities, even complex, solid or bilateral cysts, resolved with serial ultrasounds. 2. Complex-appearing cysts...
