Cesarean delivery for term breech not associated with long-term benefit [Classics Series]

1. At 2-year follow-up, planned cesarean delivery was not associated with reduction in neurodevelopmental delay compared to planned vaginal delivery for term breech malpresentation. Original...
Classics Series, Landmark Trials in Medicine

Preterm infants benefit from delayed umbilical cord clamping [Classics Series]

1. Preterm infants randomized to delayed cord clamping for 30 seconds after birth required less cardiorespiratory intervention, less supplemental oxygen and fewer blood transfusions...

Adverse pregnancy outcomes associated with thrombophilias [Classics Series]

1. The incidence of genetic thrombophilias was found to be higher in women with adverse pregnancy outcomes. Original Date of Publication: January 1999 Study Rundown: Inadequate...
Classics Series, Landmark Trials in Medicine

Behavioral intervention superior for urge incontinence [Classics Series]

1. For treatment of urgency incontinence, behavioral intervention was associated with the greatest reduction in incontinence episodes and the highest patient satisfaction rates compared...
Classics Series, Landmark Trials in Medicine

Worse side effects following transobturator sling [Classics Series]

1. Retropubic tension free vaginal tape (TVT) and transobturator tape (TOT) were associated with similar success rates for treatment of stress urinary incontinence at...
Classics Series, Landmark Trials in Medicine

The Term Breech trial: Cesarean delivery improves perinatal outcome [Classics Series]

1. Among women with term fetuses in breech malpresentation, cesarean delivery was associated with reduction in perinatal and neonatal mortality and morbidity. Original Date of...
Classics Series, Landmark Trials in Medicine

Zidovudine reduces maternal-infant HIV transmission [Classics Series]

1. Among pregnant women with HIV, antepartum, intrapartum and neonatal zidovudine therapy reduced maternal-fetal transmission of HIV by two-thirds. Original Date of Publication: November 1994 Study...
Classics Series, Landmark Trials in Medicine

Doppler velocimetry of fetal middle cerebral artery predicts anemia [Classics Series]

1. Among fetuses at risk for maternal red cell alloimmunization, peak systolic velocity in the middle cerebral artery is a sensitive predictor of moderate...
Classics Series, Landmark Trials in Medicine

The ORACLE trial: Antibiotics for preterm, prelabor rupture of membranes [Classics Series]

1. Among infants born to women with preterm, premature rupture of membranes, those whose mothers were randomized to treatment with erythromycin experienced a lower...
Classics Series, Landmark Trials in Medicine

Head cooling improves outcomes in neonatal encephalopathy [Classics Series]

1. Among term infants with neonatal encephalopathy associated with mild EEG changes, those randomized to head cooling had a reduced incidence of death and...
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