Bedaquiline monotherapy may be effective at improving multibacillary leprosy.
1. In this proof-of-concept study, bedaquiline therapy cleared Mycobacterium leprae by four weeks of treatment in patients with multibacillary leprosy....
Wellness
SEP-1 sepsis management bundle not associated with improved mortality
1. In this systematic review, there was minimal evidence of improved sepsis mortality with implementation of the Severe Sepsis and...
Esophageal candida infection associated with increased esophageal cancer risk in patients with achalasia
1. Among 234 patients with achalasia, esophageal candidiasis was identified in 12%. 2. Among patients with achalasia, prior esophageal candidiasis,...
Poor glycemic control may not be associated with increased outpatient antibiotic prescription rates
1. HbA1C levels were not associated with the number of antibiotic prescriptions in type 2 diabetic patients followed at primary...
Late-arresting attenuated parasite provides greater malaria protection than early-arresting parasite
1. In this randomized controlled trial, it was found that GA2, a late-arresting, genetically attenuated Plasmodium falciparum parasite, induced greater...
Influenza vaccination may reduce secondary infection spread amongst household contacts
1. Influenza vaccination was associated with a reduced risk of secondary influenza infections among household contacts, with an estimated effectiveness...
Poor control over clinical work associated with burnout among physicians
1. In this cross-sectional survey, poor control over patient load, team composition, and clinical schedule were each associated with burnout...
Levels Of MMP-2 and TNF-α May Be Associated With The Inflammatory Processes Underlying Schizophrenia
Inflammatory markers MMP-2 and TNF-α were higher in treatment-resistant (TRS), and chronically medicated schizophrenia (CMS) groups, respectively compared to a...
Specific Inflammatory Cytokines May Impact Depression Severity, Suicidal Ideation, And Behaviour
Interleukin-1β levels are significantly associated with depression severity, but not suicidal ideation and behaviour Tumor necrosis factor-α is significantly associated...
Internet Based Cognitive Behavioural Therapy Reduces Cardiac Anxiety And Frequency Of Chest Pains In Individuals With Non-Cardiac Chest Pains
Internet-delivered cognitive behavioral (iCBT) therapy reduced cardiac anxiety in people with non-cardiac chest pains but was not superior to psychoeducation....
