• About
  • Masthead
  • License Content
  • Advertise
  • Submit Press Release
  • RSS/Email List
  • 2MM Podcast
  • Write for us
  • Contact Us
2 Minute Medicine
No Result
View All Result

No products in the cart.

SUBSCRIBE
  • Specialties
    • All Specialties, All Recent Reports
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Pharma
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • AI Roundup
  • Pharma
  • The Scan+
  • Classics™+
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Podcasts
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • Account
    • Subscribe
    • Sign-in
    • My account
2 Minute Medicine
  • Specialties
    • All Specialties, All Recent Reports
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Pharma
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • AI Roundup
  • Pharma
  • The Scan+
  • Classics™+
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Podcasts
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • Account
    • Subscribe
    • Sign-in
    • My account
SUBSCRIBE
2 Minute Medicine
Subscribe
Home All Specialties Cardiology

Closure devices may reduce complications in percutaneous coronary intervention

bys25qthea
November 19, 2013
in Cardiology, Surgery
Reading Time: 3 mins read
0
Share on FacebookShare on Twitter

Image: PD

1. For patients undergoing percutaneous coronary intervention (PCI), vascular closure devices (VCDs) were associated with an overall reduction of vascular complications such as hematomas, pseudoaneurysms and need for transfusions.  This benefit was counterbalanced by an increased risk of retroperitoneal bleeding. 

2. The reductions in vascular complications associated with VCDs were lost in the subgroup of patients who received GP IIb/IIIa inhibitors or had BMI<25kg/m2.

Evidence Rating Level: 2 (Good) 

Study Rundown: The role of vascular closure devices (VCDs) in reducing vascular complications for patients undergoing transfermoral PCI is unclear.  This observational prospective cohort study investigated the association between the use of VCDs and vascular complications in patients undergoing emergent and non-emergent PCI between 2007-2009 in 32 Michigan hospitals.  The study found that VCDs were associated with an overall reduction in vascular complications. Analysis of the breakdown of vascular complications showed that VCDs were associated with significant reductions in hematomas and transfusions requirements.  However, VCDs were associated with a significant increase in retroperitoneal bleeding.  Furthermore, subgroup analysis showed that the benefit of VCDs were lost among patients with a BMI > 25kg/m2 as well as those on GP IIb/IIIa inhibitors.  VCDs did not have an effect on mortality.  While this study greatly benefited from rigorous matching of the study population to controls, the observational design limits its ability to draw conclusions about causation.

Click to read the study, published today in the Annals of Internal Medicine

RELATED REPORTS

PCI beneficial in patients undergoing transcatheter aortic-valve implantation

Patients with coronary artery disease have sustained elevation in blood pressure following exercise

Catheter-guided aortic valve replacement and angioplasty has favorable outcomes compared to surgical intervention

Relevant Reading: Arterial puncture closing devices compared with standard manual compression after cardiac catheterization: systematic review and meta-analysis

In-Depth [retrospective cohort]: This study reviewed 85,048 PCIs that were performed from 2007-2009 at 32 hospitals in Michigan via the Blue Cross Blue Shield of Michigan Cardiovascular Consortium.  Demographic, procedural, and angiographic information was prospectively defined and data was recorded.  The patients were identified into two groups:  (1) VCD or (2) No VCD.

Patients in both groups were were matched based on baseline variables. Cases were then reviewed for one of three endpoints:  vascular complication, transfusion, or in-hospital death.  It was found that 28,528 (37%) of patients had a VCD used and that VCD usage resulted in a significant reduction of vascular complications OR 0.78 [95% CI 0.67-0.90, p = 0.001] and specifically a decrease in hematomas OR 0.69 [95% CI 0.58-0.76, p<0.001] and pseduoanerysms OR, 0.54 [95% CI 0.38-0.76, p<0.011]. There was also decreased postprocedure transfusion OR 0.85 [95% CI 0.74-0.96, p=0.011].  Interestingly, the authors also found an associated increased risk of retroperitoneal bleeding OR, 1.57 [95% CI 1.12-2.30, p=0.009].

By Adam Whittington and Aimee Li, MD

More from this author: Home-based intervention reduces depressive symptoms in older African Americans, Self-measured blood pressure monitoring lowers pressures compared to typical clinical monitoring, Insufficient data for screening asymptomatic adults with ankle-brachial index, Arsenic exposure linked with cardiovascular disease and mortality, Increased risk of invasive meningococcal disease for patients with HIV

© 2013 2minutemedicine.com. All rights reserved. No works may be reproduced without expressed written consent from 2minutemedicine.com. Disclaimer: We present factual information directly from peer reviewed medical journals. No post should be construed as medical advice and is not intended as such by the authors, editors, staff or by 2minutemedicine.com. PLEASE SEE A HEALTHCARE PROVIDER IN YOUR AREA IF YOU SEEK MEDICAL ADVICE OF ANY SORT.  

Tags: Coronary artery diseasePCI
Previous Post

No evidence for the cognitive side-effects of statins

Next Post

Home Calculator may predict likelihood of home discharge after surgery

RelatedReports

β-blockers linked to improved survival in preserved ejection fraction heart failure
Cardiology

PCI beneficial in patients undergoing transcatheter aortic-valve implantation

March 3, 2025
Prevalence of hypertension among adolescents varies by race and BMI
Cardiology

Patients with coronary artery disease have sustained elevation in blood pressure following exercise

February 28, 2025
Drug-coated balloons are noninferior to drug-eluting stents for treatment of small vessel coronary artery disease
Cardiology

Catheter-guided aortic valve replacement and angioplasty has favorable outcomes compared to surgical intervention

February 11, 2025
Drug-coated balloons are noninferior to drug-eluting stents for treatment of small vessel coronary artery disease
Cardiology

Optical coherence tomography-guided angioplasty reduces adverse events compared to angiography guidance

October 1, 2024
Next Post
Gastric bypass surgery reduces cardio-metabolic risk factors

Home Calculator may predict likelihood of home discharge after surgery

Remote ischemic preconditioning reduced myocardial injury in CABG patients

Coronary artery calcium may indicate risk of cardiovascular disease

Polio outbreak in China halted: Case report

Polio outbreak in China halted: Case report

2 Minute Medicine® is an award winning, physician-run, expert medical media company. Our content is curated, written and edited by practicing health professionals who have clinical and scientific expertise in their field of reporting. Our editorial management team is comprised of highly-trained MD physicians. Join numerous brands, companies, and hospitals who trust our licensed content.

Recent Reports

  • Artificial intelligence based clinical decision systems are safe and effective for diabetes management
  • Epic Launchpad propels generative-AI into everyday hospital routines
  • #VisualAbstract: Routine Cerebral Embolic Protection Did Not Reduce Stroke Incidence during Transcatheter Aortic-Valve Implantation
License Content
Terms of Use | Disclaimer
Cookie Policy
Privacy Statement (EU)
Disclaimer

© 2021 2 Minute Medicine, Inc. - Physician-written medical news.

  • Specialties
    • All Specialties, All Recent Reports
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Pharma
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • AI Roundup
  • Pharma
  • The Scan
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Podcasts
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • Account
    • Subscribe
    • Sign-in
    • My account
No Result
View All Result

© 2021 2 Minute Medicine, Inc. - Physician-written medical news.