Tag: Coronary artery disease

1. The use of coronary artery calcium scoring was associated with significant improvements in the reclassification and discrimination of incident atherosclerotic cardiovascular disease. 2. Coronary artery calcium scoring may be beneficial as an adjunct to risk-enhancing factor assessment when identifying individuals at intermediate risk of atherosclerotic cardiovascular disease who would...
1. In this cohort study, 91% of patients with preserved ejection fraction heart failure had evidence of epicardial coronary artery disease and/or coronary microvascular dysfunction. 2. Due to the high prevalence of these conditions, coronary artery disease and coronary microvascular dysfunction may be unrecognized and underdiagnosed in patients hospitalized with...
1. The rate of clinical events and all-cause mortality was similar in patients with drug-coated balloon therapy compared to those with drug-eluting stent therapy. 2. Treatment with drug-coated balloons yielded non-significantly decreased rates of major bleeding and probable or definite stent thrombosis.  Evidence Rating Level: 1 (Excellent) Study Rundown: Drug-coated balloons (DCBs)...
1. Among patients who have received a saphenous vein graft during coronary bypass surgery and later experience treatment failure, deployment of a drug-eluting stent during percutaneous coronary intervention leads to more favorable outcomes than does use of a bare-metal stent. Evidence Rating Level: 1 (Excellent) Study Rundown: Though it has been...
1. Patients who received low-dose colchicine daily had a ~30% lower risk of cardiovascular events compared to those who received placebo. 2. Although the incidence of cardiovascular death was similar between groups, the colchicine group had a numerically greater number of non-cardiovascular deaths as well as all-cause deaths compared to...
1. Patients status-post placement of drug-eluting stents (DES) for acute coronary syndrome received three months of Ticagrelor and Aspirin dual-antiplatelet therapy (DAPT), followed by nine months of DAPT or Ticagrelor monotherapy. 2. At one year, patients who received Ticagrelor alone experienced significantly fewer adverse major bleeding events. There was no...
Association of a Care Bundle for Early Sepsis Management With Mortality Among Patients With Hospital-Onset or Community-Onset Sepsis 1. Sepsis bundles were not significantly associated with decreased risk of mortality or reduced vasopressor treatment time in community- or hospital-onset sepsis. 2. Components of the SEP-1 bundle, such as broad-spectrum IV antibiotic...
1. There is no significant difference in 30-day all-cause mortality between radial and femoral access for percutaneous coronary intervention (PCI) following ST-segment elevation myocardial infarction (STEMI). Evidence Rating Level: 1 (Excellent) Primary percutaneous coronary intervention (PCI) is the standard of care for achieving reperfusion in patients with ST-segment elevation myocardial infarction (STEMI)....
1. Total arterial vascularization (TAR) resulted in reduced likelihood of myocardial infarction, major cardio- and cerebrovascular events, and death compared to non-TAR in those requiring coronary artery bypass grafting. Evidence Rating Level: 2 (Good) Given the discussion surrounding multivessel coronary artery disease and the ideal conduits for coronary artery bypass grafting...
1. In this analysis of data from a prospective cohort of young adults, increased mean systolic blood pressure (SBP) and variability in SBP measurements were both linked to increased risk of cardiovascular disease (CVD) in later life. 2. Variability in SBP measurement was also associated with an increased risk of...