Tag: Coronary artery disease

1. Patients who received low-dose colchicine daily had a ~30% lower risk of cardiovascular events compared to those who received placebo. 2. Although the incidence of cardiovascular death was similar between groups, the colchicine group had a numerically greater number of non-cardiovascular deaths as well as all-cause deaths compared to...
1. Patients status-post placement of drug-eluting stents (DES) for acute coronary syndrome received three months of Ticagrelor and Aspirin dual-antiplatelet therapy (DAPT), followed by nine months of DAPT or Ticagrelor monotherapy. 2. At one year, patients who received Ticagrelor alone experienced significantly fewer adverse major bleeding events. There was no...
Association of a Care Bundle for Early Sepsis Management With Mortality Among Patients With Hospital-Onset or Community-Onset Sepsis 1. Sepsis bundles were not significantly associated with decreased risk of mortality or reduced vasopressor treatment time in community- or hospital-onset sepsis. 2. Components of the SEP-1 bundle, such as broad-spectrum IV antibiotic...
1. There is no significant difference in 30-day all-cause mortality between radial and femoral access for percutaneous coronary intervention (PCI) following ST-segment elevation myocardial infarction (STEMI). Evidence Rating Level: 1 (Excellent) Primary percutaneous coronary intervention (PCI) is the standard of care for achieving reperfusion in patients with ST-segment elevation myocardial infarction (STEMI)....
1. Total arterial vascularization (TAR) resulted in reduced likelihood of myocardial infarction, major cardio- and cerebrovascular events, and death compared to non-TAR in those requiring coronary artery bypass grafting. Evidence Rating Level: 2 (Good) Given the discussion surrounding multivessel coronary artery disease and the ideal conduits for coronary artery bypass grafting...
1. In this analysis of data from a prospective cohort of young adults, increased mean systolic blood pressure (SBP) and variability in SBP measurements were both linked to increased risk of cardiovascular disease (CVD) in later life. 2. Variability in SBP measurement was also associated with an increased risk of...
1.  A decrease in circulating progenitor cells during exercise stress-testing in patients with stable coronary artery disease is associated with worse outcomes than the presence of myocardial ischemia. Evidence Rating Level: 2 (Good) Risk stratification for stable coronary artery disease (CAD) typically involves the measurement of stress-induced myocardial ischemia, often using single-photon...
1. In this study of patients undergoing PET myocardial perfusion imaging, those with greater measured ischemia had improved overall and cardiac survival with early revascularization compared to medical therapy alone. 2. An ischemia threshold of 5% was determined, above which patients were observed to have greater benefit with early coronary...
Identification of patients and plaques vulnerable to future coronary events with near-infrared spectroscopy intravascular ultrasound imaging: a prospective, cohort study 1. NIRS imaging in patients undergoing cardiac catheterization for suspected coronary artery disease can be used in identifying high-risk non-culprit lesions contributing to future major adverse coronary events.  Evidence Rating Level:...
1. In this study of patients undergoing PET myocardial perfusion imaging, those with greater measured ischemia had improved overall and cardiac survival with early revascularization compared to medical therapy alone. 2. An ischemia threshold of 5% was determined, above which patients were observed to have greater benefit with early coronary...