• About
  • Masthead
  • License Content
  • Advertise
  • Submit Press Release
  • RSS/Email List
  • Write for us
  • Contact us
2 Minute Medicine
No Result
View All Result

No products in the cart.

SUBSCRIBE
  • Specialties
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • The Scan
  • Wellness
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • AccountLog-in/out
    • Subscribe
    • Sign-in
    • My account
2 Minute Medicine
  • Specialties
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • The Scan
  • Wellness
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • AccountLog-in/out
    • Subscribe
    • Sign-in
    • My account
SUBSCRIBE
2 Minute Medicine
Subscribe
Home All Specialties Chronic Disease

Polio outbreak in China halted: Case report

bys25qthea
November 20, 2013
in Chronic Disease, Infectious Disease, Public Health
Reading Time: 3 mins read
0
Share on FacebookShare on Twitter

Image: PD 

1. An outbreak of imported polio virus in China was stopped within 1.5 months of the index case with increased surveillance and five rounds of supplementary immunization. 

Study Rundown: Twenty-one cases of infection with poliovirus type 1 were identified in the Xinjiang region of China between July 3 and October 9, 2011. China was declared a poliomyelitis-free region in 2000, and genetic sequencing data suggested that the virus was imported from Pakistan.

The incidence of poliovirus infection in this outbreak was highest among children, especially those under 1 year of age (3.46 per 100,000). However, almost half of the cases involved people between 15 and 39 years of age (0.22 per 100,000). Supplementary vaccination was initially aimed at children under 15, but coverage was expanded to all persons under 40 once adult cases were identified. In all, 43.7 million doses of vaccine were administered.

Vaccine coverage in Xinjiang prior to the outbreak was considered low relative to other regions of China. In a sample of 2611 healthy persons of any age in southern Xinjiang, 90.4% had antibodies against poliovirus. Among children younger than 5 in the sample, only 80 to 92% had antibodies. After the first three rounds of supplementary immunization, 97.8 to 99.3% of people sampled were positive for antibodies against poliovirus, and had higher antibody titers on average than before.

Supplementary immunization was carried out using both the trivalent oral polio vaccine (OPV) and the monovalent OPV type 1 (OPV1). A 2007 study showed that the monovalent OPV1 is more effective per dose than the trivalent OPV. Thus, the monovalent OPV1 is thought to facilitate a more rapid response in the setting of an outbreak.

Although successful in this case, outbreak response is a costly endeavor that requires significant infrastructure and expertise. Not all countries are as well-equipped as China for an outbreak. Without global eradication of poliovirus, all countries continue to be at risk. Economic analyses suggest that eradication, while costly in the short-term, would ultimately cost less than a policy of control without eradication.

RELATED REPORTS

Past infection with pre-omicron variants of COVID-19 protects against re-infection

Intranasal vaccine against Bordetella pertussis invokes seronegative IgA response

Regular physical activity may improve vaccine effectiveness against COVID-19 outcomes

Click to read the study, published today in NEJM

Click to read an accompanying editorial in NEJM

Relevant Reading: Eradication versus control for poliomyelitis: an economic analysis; Poliomyelitis Prevention: Recommendations for Use of Inactivated Poliovirus Vaccine and Live Oral Poliovirus Vaccine

By Tomi Jun and Adrienne Cheung

More from this author: Early risk factor for progression of cystic fibrosis identified, Gut microbes implicated in stroke and heart attacks: new dietary link, New leukemia mutation offers therapeutic targets, Childhood ADHD associated with increased risk of suicide, A marker of aggressive liver cancer and potential therapeutic target identified

©2012-2013 2minutemedicine.com. All rights reserved. No works may be reproduced without expressed written consent from 2minutemedicine.com. Disclaimer: We present factual information directly from peer reviewed medical journals. No post should be construed as medical advice and is not intended as such by the authors, editors, staff or by 2minutemedicine.com. PLEASE SEE A HEALTHCARE PROVIDER IN YOUR AREA IF YOU SEEK MEDICAL ADVICE OF ANY SORT.  

Tags: poliovaccine
Previous Post

Coronary artery calcium may indicate risk of cardiovascular disease

Next Post

Nut consumption associated with lower overall mortality

RelatedReports

Decreased expression of nasal ACE2 may be correlated with lower prevalence of COVID-19 in children
Chronic Disease

Past infection with pre-omicron variants of COVID-19 protects against re-infection

March 28, 2023
Algorithm improves pediatric chronic cough outcomes
Infectious Disease

Intranasal vaccine against Bordetella pertussis invokes seronegative IgA response

March 22, 2023
Reduced gestational weight gain with lifestyle intervention
Chronic Disease

Regular physical activity may improve vaccine effectiveness against COVID-19 outcomes

November 28, 2022
Exercise improves aromatase inhibitor-induced arthralgia in breast cancer survivors
Wellness

Wellness Check: Exercise

November 24, 2022
Next Post
Nut consumption associated with lower overall mortality

Nut consumption associated with lower overall mortality

Stem cell enrichment of fat grafts ineffective in breast augmentation

Stem cell enrichment of fat grafts ineffective in breast augmentation

The Symplicity HTN-2 trial: Renal denervation in treatment-resistant hypertension [Classics Series]

License Our Award-Winning Physician-Written Medical News and Visual Abstracts

2 Minute Medicine is the leading authoritative medical news licensing service, and the only with reports written by practicing doctors.

LICENSE CONTENT

2MM+ Premium Access

No ads & unlimited access to all current reports, over 9000 searchable archived reports, visual abstracts, Weekly Rewinds, and the online edition of The Classics Series™ textbook.

Subscription Options
2 Minute Medicine

2 Minute Medicine® is an award winning, physician-run, expert medical media company. Our content is curated, written and edited by practicing health professionals who have clinical and scientific expertise in their field of reporting. Our editorial management team is comprised of highly-trained MD physicians. Join numerous brands, companies, and hospitals who trust our licensed content.

Recent Reports

  • Addition of fludrocortisone to hydrocortisone is beneficial in management of septic shock
  • Surveillance testing of staff at nursing facilities reduces resident COVID-19 mortality
  • Childhood maltreatment may cause mental health problems
License Content
Terms of Use | Disclaimer
Cookie Policy
Privacy Statement (EU)
Disclaimer

© 2021 2 Minute Medicine, Inc. - Physician-written medical news.

  • Specialties
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • The Scan
  • Wellness
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • Account
    • Subscribe
    • Sign-in
    • My account

© 2021 2 Minute Medicine, Inc. - Physician-written medical news.

Want more physician-written
medical news?

Join over 10 million yearly readers and numerous companies. For healthcare professionals
and the public.

Subscribe for free today!

Subscription options