• About
  • Masthead
  • License Content
  • Advertise
  • Submit Press Release
  • RSS/Email List
  • Write for us
  • Contact us
2 Minute Medicine
No Result
View All Result

No products in the cart.

SUBSCRIBE
  • Specialties
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • Wellness
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • AccountLog-in/out
    • Subscribe
    • Sign-in
    • My account
2 Minute Medicine
  • Specialties
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • Wellness
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • AccountLog-in/out
    • Subscribe
    • Sign-in
    • My account
SUBSCRIBE
2 Minute Medicine
Subscribe
Home All Specialties Obstetrics

Continued versus discontinued oxytocin stimulation in the active phase of labour

byBrian DoughertyandAlex Chan
April 19, 2021
in Obstetrics
Reading Time: 2 mins read
0
Share on FacebookShare on Twitter

RELATED REPORTS

Postpartum patients may be at an increased risk of intrauterine device-related perforation

2 Minute Medicine Rewind June 6, 2022

Presence of second midwife during the second active stage of labour reduces the risk of severe perineal trauma

1. Among pregnant women, discontinuing the administration of oxytocin during the active phase of labor is associated with a small, absolute increase in the risk of cesarean delivery but significantly reduces the risk of uterine hyperstimulation and abnormal fetal heart rate.

Evidence Level Rating: 1 (Excellent)

About a quarter of all term pregnancies are induced, often with oxytocin stimulation. The use of oxytocin, however, carries with it a risk of hyperstimulation, which may lead to emergent cesarean for fetal indications secondary to uterine hyperstimulation. Recent evidence suggests that once a woman is in active labor, the labor will continue even if oxytocin is stopped; little of this evidence, though, is supported by randomized trials. As such, the aim of this double-blind, randomized controlled trial was to test whether discontinuation of oxytocin stimulation once the active phase of labor is reached reduces the overall cesarean rate. 607 women were randomized to the discontinued cohort (mean [SD] age = 31.0 [4.9] years) and 591 to the continued cohort (mean [SD] age = 31.3 [4.9] years). There was no significant difference in the rate of cesarean delivery between the discontinued (16.6%) and continued cohorts (14.2%) (RR 1.17 95% CI 0.90 to 1.53). The prespecified noninferiority testing was inconclusive (p = 0.70). Among parous women without prior cesarean, however, the risk of cesarean was substantially higher in the discontinued cohort (7.5%) compared with the continued cohort (0.6%) (RR 11.6, 95% CI 1.15 to 88.7). When reviewing secondary outcomes, it was found that the discontinuation of oxytocin was associated with a longer duration of labor, a reduced risk of uterine hyperstimulation, and a reduced risk of fetal heart rate abnormalities. There were similar rates of other adverse maternal and neonatal outcomes between the two groups. In all, this study suggests that the discontinuation of oxytocin stimulation during the active phase of labor is associated with a small, absolute increase in the risk of cesarean delivery but significantly reduces the risk of uterine hyperstimulation and abnormal fetal heart rate.

Click to read the study in BMJ

Image: PD

©2020 2 Minute Medicine, Inc. All rights reserved. No works may be reproduced without expressed written consent from 2 Minute Medicine, Inc. Inquire about licensing here. No article should be construed as medical advice and is not intended as such by the authors or by 2 Minute Medicine, Inc.

Tags: labourobstetrics
Previous Post

2 Minute Medicine Rewind April 19, 2021

Next Post

Tdap vaccine during pregnancy not linked to adverse childhood health outcomes

RelatedReports

AAP policy update recommends first-line contraceptives, addresses special populations
Emergency

Postpartum patients may be at an increased risk of intrauterine device-related perforation

June 15, 2022
Weekly Rewinds

2 Minute Medicine Rewind June 6, 2022

June 6, 2022
Women electing abortion more likely to be victims of domestic violence
Chronic Disease

Presence of second midwife during the second active stage of labour reduces the risk of severe perineal trauma

April 7, 2022
Poverty, preterm birth demonstrate additive effect on cognition
Chronic Disease

2 Minute Medicine Rewind March 28th, 2022

March 28, 2022
Next Post
Compliance-linked incentives increase infant immunizations rates in rural India

Tdap vaccine during pregnancy not linked to adverse childhood health outcomes

Patients with low back pain or pain at multiple sites at highest risk for chronic opioid use

Hospitalized patients with substance use disorder benefit from navigation services

Reducing primary care physician shortage in low-density areas increases life expectancy

License Our Award-Winning Physician-Written Medical News and Visual Abstracts

2 Minute Medicine is the leading authoritative medical news licensing service, and the only with reports written by practicing doctors.

LICENSE CONTENT

2MM+ Premium Access

No ads & unlimited access to all current reports, over 9000 searchable archived reports, visual abstracts, Weekly Rewinds, and the online edition of The Classics Series™ textbook.

Subscription Options
2 Minute Medicine

2 Minute Medicine® is an award winning, physician-run, expert medical media company. Our content is curated, written and edited by practicing health professionals who have clinical and scientific expertise in their field of reporting. Our editorial management team is comprised of highly-trained MD physicians. Join numerous brands, companies, and hospitals who trust our licensed content.

Recent Reports

  • Vitamin and mineral supplementation associated with minimal to no benefit in the primary preventing of cardiovascular disease and cancer – US Preventative Services Task Force
  • RSVpreF vaccine prevents symptomatic respiratory syncytial virus infection
  • Incidence of Kawasaki disease found to be lower during the COVID-19 pandemic in the United States
License Content
Terms of Use | Disclaimer
Cookie Policy
Privacy Statement (EU)
Disclaimer

© 2021 2 Minute Medicine, Inc. - Physician-written medical news.

  • Specialties
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • Wellness
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • Account
    • Subscribe
    • Sign-in
    • My account

© 2021 2 Minute Medicine, Inc. - Physician-written medical news.