• About
  • Masthead
  • License Content
  • Advertise
  • Submit Press Release
  • RSS/Email List
  • Write for us
  • Contact us
2 Minute Medicine
No Result
View All Result

No products in the cart.

SUBSCRIBE
  • Specialties
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • Wellness
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • AccountLog-in/out
    • Subscribe
    • Sign-in
    • My account
2 Minute Medicine
  • Specialties
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • Wellness
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • AccountLog-in/out
    • Subscribe
    • Sign-in
    • My account
SUBSCRIBE
2 Minute Medicine
Subscribe
Home All Specialties Infectious Disease

Hepatitis C screening in prisons may reduce transmission and infection rates

byNicholas WoolfandSai Folmsbee
November 24, 2015
in Infectious Disease, Public Health
Reading Time: 2 mins read
0
Share on FacebookShare on Twitter

1. According to a model simulation, implementation of an opt-out prison screening protocol would diagnose at least 81,000 hepatitis C cases over the next 30 years.

2. Opt-out screening would also reduce hepatitis C-associated healthcare costs by at least $510 million over 30 years.

Evidence Rating Level: 2 (Good)

Study Rundown: In the U.S. prison population, many inmates are seropositive for hepatitis C virus (HCV), where the most common mode of transmission is intravenous drug use. Despite its high prevalence, screening for HCV is only conducted in a quarter of prisons nationwide. The current study used a microsimulation model to compare risk-based and opt-out HCV screening approaches. Primary outcome measures included prevention of HCV transmission and associated disease, costs, quality-adjusted life years (QALYs), and impact on total prison budget. The model found that an opt-out protocol would diagnose more new HCV cases, prevent more HCV infections, and reduce healthcare costs associated with HCV more than a risk-based protocol. Although all of the opt-out screening strategies proposed were more expensive than the risk-based strategy, they were just as cost-effective; all strategies had incremental cost-effectiveness ratios (ICERs) below $50,000 per additional QALY after sensitivity analyses. This study was limited primarily in that its model relied on many assumptions about HCV screening practices and transmission rates in U.S. prisons. However, it is clear that hepatitis C screening may reduce transmission and infection in prisoner populations.

Click to read the study published today in the AIM

Relevant Reading: Ending hepatitis C in the United States: the role of screening

In-Depth [model simulation]: The model used in this study was developed to simulate HCV transmission, natural history, screening in inmates and treatment. It also estimated the number of inmates moving between prison and the general community. All of these aspects of the model were projected on a monthly basis for the next 30 years. The results of the simulation showed that risk-based screening for 1 year would diagnose 41 900 (95%CI 40 700-43 200) new HCV cases over 30 years, while 1-year, 5-year and 10-year opt-out screening strategies would diagnose 81 100 (95%CI 79 600-82 700), 106 600 (95%CI 104 700-108 500) and 122 700 (95%CI 120 800-124 600) new HCV cases, respectively, over the same time period. The 1-year risk based, 1-year opt-out, 5-year-opt out and 10-year opt-out strategies would prevent 5 500 (95%CI 4 400-6 600), 8 000 (95%CI 6 800-9 000), 10 900 (95%CI 9 700-12 000) and 12 700 (95%CI 11 500-13 900) new HCV infections, respectively, compared to no screening. Notably, 89%-92% of these prevented infections would have affected patients in the general population. Lastly, compared with no screening program, the 1-year risk based, 1-year opt-out, 5-year opt-out and 10-year opt-out programs would decrease HCV-associated healthcare costs by $260 million (95%CI $220-$300 million), $510 million (95%CI $470-$560 million), $680 million (95%CI $620-$740 million) and 760 million (95%CI $700-$820 million), respectively.

RELATED REPORTS

Accessible hepatitis C care for people who inject drugs provide significantly higher rates of cure compared to conventional care

Demographic trends associated with increased maternal & neonatal Hepatitis C cases over 10 years

Adenovirus encoding hepatitis C virus vaccine is safe but effectiveness is unclear

Image: CC/Wiki

©2015 2 Minute Medicine, Inc. All rights reserved. No works may be reproduced without expressed written consent from 2 Minute Medicine, Inc. Inquire about licensing here. No article should be construed as medical advice and is not intended as such by the authors or by 2 Minute Medicine, Inc.

Tags: hepatitis C
Previous Post

2 Minute Medicine Rewind November 15 – November 22, 2015

Next Post

Lactation after gestational diabetes may decrease risk of type 2 diabetes

RelatedReports

Large spike in drug use-associated infective endocarditis linked with opioid epidemic
Gastroenterology

Accessible hepatitis C care for people who inject drugs provide significantly higher rates of cure compared to conventional care

March 17, 2022
Social networks play key roles in parental vaccination decisions
Chronic Disease

Demographic trends associated with increased maternal & neonatal Hepatitis C cases over 10 years

November 1, 2021
Compliance-linked incentives increase infant immunizations rates in rural India
Infectious Disease

Adenovirus encoding hepatitis C virus vaccine is safe but effectiveness is unclear

February 10, 2021
Screening insufficient for newborns exposed to hepatitis C virus
Cardiology

Expanding heart transplant in the era of direct-acting antiviral therapy for hepatitis C

December 28, 2019
Next Post
USPSTF finds insufficient evidence for screening for iron deficiency anemia during pregnancy

Lactation after gestational diabetes may decrease risk of type 2 diabetes

Adverse pregnancy outcomes associated with thrombophilias [Classics Series]

Association of bacterial vaginosis and low birthweight infants [Classics Series]

Progesterone injections for short cervix do not reduce preterm birth

Vaginal progesterone shows no benefit for preventing unexplained recurrent miscarriages: The PROMISE study

License Our Award-Winning Physician-Written Medical News and Visual Abstracts

2 Minute Medicine is the leading authoritative medical news licensing service, and the only with reports written by practicing doctors.

LICENSE CONTENT

2MM+ Premium Access

No ads & unlimited access to all current reports, over 9000 searchable archived reports, visual abstracts, Weekly Rewinds, and the online edition of The Classics Series™ textbook.

Subscription Options
2 Minute Medicine

2 Minute Medicine® is an award winning, physician-run, expert medical media company. Our content is curated, written and edited by practicing health professionals who have clinical and scientific expertise in their field of reporting. Our editorial management team is comprised of highly-trained MD physicians. Join numerous brands, companies, and hospitals who trust our licensed content.

Recent Reports

  • Stereotactic body radiotherapy as a state of the art treatment option in inoperable non-small cell lung cancer [Classics Series]
  • Health system-based care associated with better treatment use and high rates of tobacco abstinence at 3 months post-discharge in hospitalized smokers
  • APOEε4 genotype may increase risk of chronic traumatic encephalopathy following repetitive head impact
License Content
Terms of Use | Disclaimer
Cookie Policy
Privacy Statement (EU)
Disclaimer

© 2021 2 Minute Medicine, Inc. - Physician-written medical news.

  • Specialties
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • Wellness
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • Account
    • Subscribe
    • Sign-in
    • My account

© 2021 2 Minute Medicine, Inc. - Physician-written medical news.